research FDA Declines Approval of Testosterone Drug for Third Time
The FDA rejected a testosterone drug again due to safety concerns.
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research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
research To Study Hypoactive Sexual Desire Disorder in a Fragile X Carrier Female Successfully Treated with Local Testosterone Application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research Preparation of 3H-Labelled Testosterone Metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta Vulgaris L. Extract in Testosterone-Induced Alopecia
Beetroot extract nanogel may help treat hair loss caused by testosterone.
research New-Onset Androgenic Alopecia Following Human Chorionic Gonadotropic Diet and Testosterone Pellet Implantation
The hCG diet and testosterone therapy can cause hair loss in some people.
research Effect of Cosmetic Hair Treatment and Natural Hair Color on Hair Testosterone Concentrations
Cosmetic hair treatments can increase hair testosterone levels, while natural hair color does not affect it.
research Two Transgender Men Receiving Subdermal Testosterone Pellets for Gender Affirmation
Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.
research Testosterone, Sex Hormone-Binding Globulin, and Dehydroepiandrosterone Levels and Cervical Length of Egyptian Women with a History of Recurrent Miscarriages, Polycystic Ovary Syndrome, and Without the Conditions at Three Stages of Pregnancy
High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.
research Effect of Eurycoma Longifolia Extract on Testosterone Synthesis in TM3 Leydig Cells Under Oxidative Stress
Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Change in Hair Growth-Related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-Alpha Reductase Inhibitors – Dutasteride and Finasteride – in the Presence of Testosterone
Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
research Regulatory Effect of Cannabidiol on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells
CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
research Testosterone and Progesterone Levels, Gene Expression of Androgen and Progesterone Receptors in Albino Male Rats Treated with Phenolic Flower Extract of Hibiscus Rosa-Sinensis L
The flower extract lowered testosterone, progesterone, and related gene expression in male rats.
research Postmenopausal Ovarian Hyperthecosis Associated with Rapid Testosterone Excess
Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
research Prostaglandin D2-Enhanced Testosterone Metabolism in Human Keratinocytes Is Mediated by Reactive Oxygen Species
Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.
research A Preliminary Study on the Effect of Biochanin A on Hair Growth in Testosterone-Induced Alopecia Mice
Biochanin A promotes hair growth in mice with testosterone-induced hair loss.
research Effect of Medicated Oil of Martynia Annua Leaves and Fruits on Testosterone Induced Alopecia in Mice
Medicated oil from Martynia annua leaves and fruits helps prevent hair loss caused by testosterone in mice.
research Comparison of Alopecia Severity and Blood Level of Testosterone in Men Suffering Schizophrenia with Control Group
Men with more severe hair loss had a lower risk of schizophrenia, but hair loss and testosterone levels were not linked.
research Testosterone And Dihydrotestosterone Production In Genetically Furless And Furred Male Rabbits And Effects On Growth
Furless male rabbits grew slightly faster and heavier than furred ones, but testosterone levels were not the cause.
research A Rare Case of Poorly-Differentiated Endometrial Carcinoma in a Female-to-Male Transgender Man on Testosterone Therapy
Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.
research Low Serum Zinc Concentration Is Associated With Low Serum Testosterone But Not Erectile Function
Low zinc levels are linked to low testosterone but not to sexual problems.
research Letter to the Editor on COVID-19 Infection in Men on Testosterone Replacement Therapy
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research Testosterone Replacement in the Setting of Finasteride Therapy: A Therapeutic Dilemma
research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats
High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Toxoplasma Gondii Infection and Testosterone Alteration: A Systematic Review and Meta-Analyses
Toxoplasma gondii infection may increase testosterone levels in males.
research Behavioral and Hormonal Changes Following the Continuous Administration of Testosterone in Adult Female Capuchin Monkeys (Sapajus Libidinosus)
Testosterone increases sexual behavior in female capuchin monkeys.
research Effects of Depot Medroxyprogesterone Acetate, the Copper IUD, and the Levonorgestrel Implant on Testosterone, Sex Hormone Binding Globulin, and Free Testosterone Levels: Ancillary Study of the ECHO Randomized Clinical Trial
The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
research Testosterone Hormone: Clinical Indications, Dysregulation, and Therapeutic Methods
Testosterone is vital for male health, and its deficiency is linked to aging and common health issues.