Testosterone and Progesterone Levels, Gene Expression of Androgen and Progesterone Receptors in Albino Male Rats Treated with Phenolic Flower Extract of Hibiscus Rosa-Sinensis L
April 2020
in “
Medico-Legal Update
”
Studysummary This study found that phenolic extract from Hibiscus rosa-sinensis flowers significantly decreased testosterone, progesterone levels, and androgen receptor expression in male rats over 60 days.
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The study evaluated the effects of phenolic extract from Hibiscus rosa-sinensis L. flowers on testosterone and progesterone levels, as well as gene expression of androgen and progesterone receptors in 32 albino male rats. Results indicated a significant decrease (p<0.05) in testosterone and progesterone levels, and a significant reduction (p<0.05) in the expression of androgen and progesterone receptors in testicular cells of treated rats compared to control groups after 30 and 60 days of treatment with 300 mg/kg/day of the extract.
