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The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.

Microemulsions could improve how drugs are delivered and absorbed in the body.

Stump-tailed macaque best for researching hair loss causes and treatments.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

New treatments for hair loss are being developed using molecular biology.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Cannabidiol shows promise as an effective treatment for acne.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The new topical growth hormone formula has high skin penetration and bioavailability.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.