May 2012 in “Reactions Weekly” A man developed hair loss from testosterone treatment but improved with additional medication.
In this study, oral testosterone administered three times daily normalized serum testosterone levels in men with experimentally induced hypogonadism over nine days and significantly reduced SHBG.
Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.
January 2005 in “Journal of Investigative Medicine” This study found that testosterone therapy improved physical performance, strength, lean body mass, and serum cholesterol in older men with low testosterone levels, with or without the addition of finasteride.
This study suggests that the negative impact of high-dose Finasteride on male reproductive function may be mitigated by concurrent administration with TU.
January 2005 in “Journal of Investigative Medicine” Testosterone boosts physical performance, grip strength, and lean body mass in older men with low testosterone.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
August 2003 in “Oncology Times” This article discusses the considerations and challenges surrounding a proposed large-scale trial on testosterone-replacement therapy in older men and reports no new results.
January 2003 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This review discusses the dermatological impacts of hypogonadism in men, including skin thinning, reduced body hair, and skin reactions to testosterone therapy, but reports no new clinical results.
This article discusses the complexities of diagnosing hyperandrogenism in women and reviews potential treatments, such as antiandrogens and finasteride, but reports no new clinical findings.
August 1994 in “Journal of dermatological science” Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.
January 1994 in “JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS” Testosterone and fleece-flower root affect mouse hair growth.
August 1993 in “Journal of Dermatological Science” Cyclosporin and minoxidil promote hair growth.
May 1963 in “American journal of obstetrics and gynecology” This study found that a single 2 ml injection of TEEV every 4 weeks offers similar beneficial effects with fewer side effects compared to injecting the same dose every 2 weeks in postmenopausal women.
April 2023 in “International Journal of Pharmaceutics” In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride improved knee extensor strength and muscle size in men with impaired gait after chronic incomplete spinal cord injury.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride improved body composition in men with impaired gait and low to low-normal testosterone after chronic incomplete spinal cord injury.
March 2023 in “Archives of Physical Medicine and Rehabilitation” This pilot study suggests that high-dose testosterone plus finasteride increased lower-extremity bone mineral density in men with impaired gait and low to low-normal testosterone following chronic incomplete spinal cord injury.
November 2022 in “Journal of Investigative Dermatology” This study found that testosterone impacts hair follicles from different scalp regions differently in male pattern androgenetic alopecia, challenging the belief that occipital scalp follicles are androgen-insensitive.
June 2022 in “International journal of drug delivery technology” This study found that Convolvulus arvensis ethanolic extract may promote hair growth and reduce hair loss in albino mice with testosterone-induced baldness by increasing follicular density and the anagen/telogen ratio.
July 2021 in “British Journal of Dermatology” Low testosterone levels may contribute to female pattern hair loss in men.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
December 2020 in “Journal of Skin and Sexually Transmitted Diseases” This study found no significant correlation between serum testosterone or DHEAS levels and the severity of acne or FPHL in a localized female population, but noted most patients had low testosterone levels.
This study suggests that 5AR inhibitors may reverse decreased expression of growth factor genes in human hair follicles under testosterone stimulation, indicating involvement of type I 5AR in hair growth.
June 2018 in “The Journal of Sexual Medicine” In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
August 1993 in “Journal of Dermatological Science” Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
May 2007 in “The Journal of Urology” Finasteride lowers PSA levels in men, certain factors increase testicular cancer risk, and current guidelines for penile cancer may lead to unnecessary surgeries.
August 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that Finasteride at doses of 5 mg or higher may reduce the expression of key spermatogenesis biomarkers, potentially impacting male fertility in mice.
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October 1983 in “Archives of Dermatology” This study found that free testosterone levels were a more sensitive indicator of hyperandrogenism in women with acne than total testosterone levels.