TLDR Testosterone therapy can improve skin and hair in men with low testosterone but may cause skin irritation with certain treatments.
The document discussed the effects of testosterone replacement therapy on the skin, hair, and appendages in men with hypogonadism. It was noted that hypogonadism led to dermatological changes such as thinner skin, increased wrinkling, and reduced body hair, without the typical male pattern baldness. Prepubertal hypogonadism resulted in sebostase due to lack of sebaceous gland stimulation and a lack of increased pigmentation in genital skin. While reactions to oral or intramuscular androgens were rare, non-scrotal transdermal testosterone therapies more frequently caused irritative or allergic skin changes.
21 citations
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May 2001 in “PubMed” Androgen hormones affect hair growth and oil production, influencing conditions like hair loss and acne.
198 citations
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January 1998 in “Dermatology” The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
23 citations
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August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
19 citations
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May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
February 2023 in “IntechOpen eBooks” Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.