research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
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research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research Non-Classic Congenital Adrenal Hyperplasia
Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
research Abstracts from the ASA 40th Annual Meeting
HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Presentation of a Meningioma in a Transwoman After Nine Years of Cyproterone Acetate and Estradiol Intake: Case Report and Literature Review
A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.
research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Tissue Engineering of the Reproductive System
Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Medical Care for Children and Adolescents with Gender Dysphoria and Gender Inconsistency in Light of Current Recommendations: How to Implement the 'Primum Non Nocere' Principle?
The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
research Characteristics of Finasteride Users in Comparison with Nonusers: A Nordic Nationwide Study Based on Individual-Level Data from Denmark, Finland, and Sweden
Finasteride users have higher odds of certain health issues and lower odds of specific lifestyle factors compared to nonusers.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Genetic Regulation of the Androgen Receptor: A Study of Testicular Feminization in the Mouse
The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
research Anabolic Effect of Dihydrotestosterone in Testicular Feminization Syndrome
Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.
research Telogen Effluvium on the Unilateral Flank with Testicular Tumor in a Dog
A dog's hair loss was caused by a hormone-secreting testicular tumor.
research Association Between Male Pattern Baldness and Testicular Germ Cell Tumor: A Meta-Analysis
Baldness may lower the risk of testicular cancer.
research Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Spontaneous Lesions of Endangered Geriatric Julia Creek Dunnarts (Sminthopsis Douglasi, Archer 1979) with Emphasis on Reproductive Pathology
Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.
research Recent Advances in Understanding and Managing Male Infertility
Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.
research Men's Health
The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.