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Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Some common medications can harm male fertility, but many effects can be reversed.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.