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DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Testosterone is crucial for development, growth, and various body functions in mammals.

Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

Finasteride may increase suicide risk; more research needed.

Different hair loss types need accurate diagnosis for proper treatment.

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Finasteride may affect PNMT, causing side effects.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Use trichoscopy to diagnose hair loss; treat with minoxidil, finasteride, or dutasteride; consider platelet-rich plasma and spironolactone.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.