January 2024 in “Annals of Agricultural and Environmental Medicine” This study observed that LED therapy improved hair regrowth and reduced hair loss in patients with post-COVID telogen effluvium, with or without androgenetic alopecia, compared to those who did not receive LED treatment.
July 2025 in “JAAD Case Reports” A thorough assessment and combined treatment are crucial for managing complex alopecia, especially in patients with skin of color.
This review reported that alopecia prevalence and psychosocial impacts vary significantly among migrant and ethnic minority communities due to diverse genetic, environmental, and cultural factors, highlighting needs for culturally competent care and stigma reduction to address disparities and improve access.
February 2024 in “Biomedicines” This review examines the hormonal causes of hair loss, noting how androgen excess can lead to follicle miniaturization and linking estrogen deficiency and thyroid dysfunction to common alopecia types. It further discusses hormonal treatments such as finasteride, dutasteride, and spironolactone.
September 2023 in “International Journal of Trichology” Oral Vitamin D can improve hair density and reduce hair loss in Telogen Effluvium patients.
In this observational study, nine out of ten patients developed Telogen Effluvium after mild COVID-19 symptoms, with hair shedding starting on average 73 days following infection.
January 2021 in “Turkiye Klinikleri Journal of Dermatology” This study found that male patients with hair loss often had lower levels of vitamins D and B12, suggesting these deficiencies should be tested for in treatment evaluations.
June 2020 in “Journal of clinical and investigative dermatology” In this study, women with diffuse hair loss reported that Proteoglycan Replacement Therapy with Nourkrin® improved hair growth and appearance, boosting their confidence and satisfaction with the treatment.
May 2024 in “International Journal of Molecular Sciences” This study found that injecting mouse hair follicle-derived mesenchymal stem cells (moMSCORS) into C57BL/6 mice reduced the incidence and severity of type 1 diabetes by modulating immune responses, suggesting potential for therapeutic use due to their immunosuppressive effects.
24 citations
,
October 2017 in “Scientific reports” This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.
2 citations
,
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
January 2015 in “Durham e-Theses (Durham University)” This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.
This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
159 citations
,
November 2007 in “American Journal of Pathology” In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
144 citations
,
July 2002 in “Clinical and Experimental Dermatology” This article reviews the concept of telogen effluvium and emphasizes the importance of identifying triggers and using diagnostic investigations to determine the cause of hair loss, without reporting new results.
July 2023 in “Письма в Вавиловский журнал генетики и селекции” This review article discusses studies showing that extracellular nucleic acids play a role in tissue regeneration by triggering sterile inflammation through endosomal toll-like receptor activation, but notes that the regulatory transition from inflammation to proliferation phases remains incompletely understood.
127 citations
,
January 2013 in “PLOS ONE” This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.
6 citations
,
August 2009 in “Arquivos Brasileiros de Ciências da Saúde” This study created a novel classification for dermatological and cosmiatric changes caused by cancer treatments, categorizing them as triggered, exacerbated, or unrelated to the treatment.
January 2024 in “Wiadomości Lekarskie” In this overview of COPD exacerbations, it was reported that these events, often triggered by respiratory viruses, not only worsen symptoms but also increase the risk of cardiac events, highlighting the importance of early detection and prevention strategies such as vaccinations and new biologic therapies.
January 2001 in “Biomedical Research” This study observed that PAD type III and trichohyalin are expressed earlier than their deiminated form during the first and second hair cycles in rat hair follicles, indicating a potential additional factor is involved in triggering deimination.
October 2025 in “Brazilian Journal of Hair Health” This narrative review identifies telogen effluvium as a growing concern linked to weight-loss interventions, such as GLP-1 receptor agonists and bariatric surgery, attributing hair loss to systemic and metabolic stress rather than permanent hair follicle damage.
39 citations
,
April 2024 in “Frontiers in Endocrinology” This study reviews the causes, mechanisms, and treatments for thin endometrium, highlighting multiple contributing factors such as hormonal influences, long-term oral contraceptive use, and uterine inflammation, while noting unclear mechanisms in promising therapeutic strategies like pharmacological treatments and regenerative medicine approaches.
January 2026 in “Bandung Conference Series Medical Science” In this study, researchers observed no significant association between hijab use and telogen effluvium among female medical students, despite a relatively high incidence of hair loss in this population.
4 citations
,
November 2024 in “International Journal of Molecular Sciences” This review explores whether SARS-CoV-2 could trigger or worsen α-synucleinopathies, like Parkinson's disease, by affecting α-synuclein misfolding and aggregation, potentially linking COVID-19 with the development of parkinsonism-like symptoms.
27 citations
,
September 2021 in “Microbiology Spectrum” This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.
August 2025 in “Research Square (Research Square)” This study observed that among male patients who experienced telogen effluvium after platelet-rich plasma treatment for androgenic alopecia, there were elevated levels of TNF-α, androgen receptors, and altered 5α-reductase gene expression, suggesting these factors as potential contributors to this unintended outcome.
90 citations
,
December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
March 2024 in “Cell communication and signaling” This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.
15 citations
,
May 2017 in “Lasers in Medical Science” This study found that low-level laser treatment may promote hair regrowth in mice by activating the Wnt10b/ß-catenin pathway and inducing the anagen phase of hair follicles.