SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms

    November 2024 in “ International Journal of Molecular Sciences ”
    Joanna Motyl, Grażyna Gromadzka, Grzegorz A. Czapski, Agata Adamczyk
    Studysummary This review explores whether SARS-CoV-2 could trigger or worsen α-synucleinopathies, like Parkinson's disease, by affecting α-synuclein misfolding and aggregation, potentially linking COVID-19 with the development of parkinsonism-like symptoms.
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    Research cited in this study 2

    1. COVID-19 in Adult Patients With Pre-Existing Chronic Cardiac, Respiratory, and Metabolic Disease: A Critical Literature Review With Clinical Recommendations Tropical Diseases Travel Medicine and Vaccines · 2020
    2. A Preliminary Observation: Male Pattern Hair Loss Among Hospitalized COVID-19 Patients in Spain – A Potential Clue to the Role of Androgens in COVID-19 Severity Journal of Cosmetic Dermatology · 2020