Role of Extracellular Nucleic Acids in Regeneration Processes

The review article discusses the role of extracellular nucleic acids in tissue regeneration, highlighting their function as alarmins that activate toll-like receptors (TLRs) to induce sterile inflammation necessary for damage repair. Proper regulation of inflammation is crucial, as dysregulation can lead to pathologies. The transition from inflammation to proliferation is critical and complex, though the regulatory mechanisms are not yet fully understood.