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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Surgeons make more mistakes in hair transplant procedures as they get tired or do more work.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

IFHUT shows better hair growth than FUE, but needs improvements in positioning, speed, and accuracy.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Hair restoration surgery has evolved over time, with a focus on natural-looking results and managing patient expectations, while also considering potential complications and the lifelong progression of male pattern baldness.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Exosomes from umbilical cord cells fix hearing loss and damaged ear hair cells in mice.

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

DNA methylation changes are linked to hair growth cycles in goats.

Surgical methods for hair loss due to scarring should be chosen based on the size, location, and shape of the area, with most patients seeing good results.

Surgery for scar-related hair loss on the scalp and eyebrow was successful in 75% of patients.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.