1 citations
,
February 2023 in “Frontiers in Endocrinology” This study demonstrates that combining gene expression data with a random forest algorithm provides highly accurate diagnosis of childhood growth hormone deficiency, showing potential utility in distinguishing it from non-GHD short stature.
1 citations
,
March 2019 in “Chinese Medical Journal” This study identified a small population of PAX3+/CD34+ cells in human foreskin tissue that may serve as transition cells between melanocyte stem cells and hair follicle stem cells, characterized by specific marker expressions.
197 citations
,
June 2009 in “American journal of human genetics” This study found that previously undescribed WNT10A mutations are a prominent cause of various forms of ectodermal dysplasia, including OODD and Schöpf-Schulz-Passarge syndrome, with gender-specific phenotypic effects noted.
68 citations
,
September 1990 in “Biochemical Pharmacology” This study found that minoxidil is bioactivated through sulfation by the phenol-sulfating form of phenol sulfotransferase in human liver.
65 citations
,
January 2013 in “Cochrane library” This review found that infliximab, golimumab, and some forms of radiotherapy significantly improved nail psoriasis compared to controls, although they could have serious adverse effects and are not commonly used specifically for nail issues.
34 citations
,
August 1966 in “Experimental cell research” This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
30 citations
,
November 2013 in “Journal of The American Academy of Dermatology” This study reported that patterns of fibrosis identified through elastin staining may help distinguish specific forms of primary cicatricial alopecia in biopsy specimens, with certain patterns suggesting particular diagnoses.
4 citations
,
March 2019 in “Acta Chromatographica” This study developed two sensitive chromatographic methods for determining finasteride and tamsulosin hydrochloride in pharmaceutical forms, validated against International Conference on Harmonisation guidelines.
3 citations
,
May 2023 in “Precision clinical medicine” This study analyzed gene expression data to identify key genes involved in severe forms of alopecia areata, discovering four immune monitoring genes (LGR5, SHISA2, HOXC13, S100A3) with potential for early diagnosis and better understanding of the disease's biological mechanisms.
2 citations
,
May 2018 in “Expert opinion on orphan drugs” This review discusses Omenn syndrome, a form of severe combined immunodeficiency, highlighting its immunopathology and genetic defects without presenting new clinical results.
1 citations
,
September 2023 in “JCEM case reports” This case series observed the efficacy of GnRH analogues in diagnosing and treating various forms of ovarian hyperandrogenism, illustrating their role in symptom management without surgery, particularly for benign conditions and refractory androgen excess.
April 2026 in “International Journal of Drug Delivery Technology” This study found trichoscopy to be a reliable non-invasive method for diagnosing various forms of alopecia, aiding in clinical management and reducing the need for biopsies in a hospital-based setting with 90 patients, including those with uncertain diagnoses.
July 2018 in “Elsevier eBooks” This review discusses telogen effluvium, a common form of hair loss, and reports no new clinical results; the authors outline possible causes, typical prognosis, and management strategies.
329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
51 citations
,
August 2013 in “Journal of Investigative Dermatology” This study demonstrated that cultured human dermal papilla cells can induce full hair follicle formation when combined with neonatal foreskin keratinocytes in a grafted dermal-epidermal construct on mice.
June 2026 in “International Journal of Drug Delivery Technology” This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.
June 2021 in “International journal of research in dermatology” This report describes a child and his father with hereditary hypotrichosis simplex, an uncommon isolated form of hair loss, with no other ectodermal or systemic abnormalities noted.
38 citations
,
November 2016 in “Aaps Pharmscitech” This study found that the nanostructured lipid carrier formulation with a 70:30 solid to liquid lipid ratio significantly increased the dissolution rate, entrapment efficiency, and stability of spironolactone compared to its raw form.
291 citations
,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that rat whisker follicle stem cells can be expanded in culture and transplanted to form functional hair follicles, demonstrating their multipotency and potential for regenerative medicine.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
53 citations
,
June 2012 in “Annales d'Endocrinologie” This review discusses the range and causes of adipose tissue diseases, emphasizing genetic and acquired forms of lipodystrophy, but it reports no new clinical results.
39 citations
,
November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
29 citations
,
May 2018 in “Clinical Endocrinology” This review discusses the differential diagnosis of low-renin hypertension and highlights recent genetic discoveries related to familial forms, but it presents no new clinical results.
11 citations
,
January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
1 citations
,
January 2022 in “Medical Science” This study found that patients with Alopecia Areata, particularly those with severe forms, exhibited higher triglycerides, cholesterol, and low-density lipoproteins, suggesting increased cardiovascular risk factors.
February 2026 in “Nature Synthesis” In this study, researchers introduced a visible-light-mediated intramolecular cycloaddition method that selectively forms 6-azabicyclo[3.1.1]heptanes, suggesting these structures could offer promising new scaffolds for drug discovery and medicinal chemistry.
August 2025 in “Frontiers in Immunology” This meta-analysis found that patients with alopecia areata, particularly those with more extensive forms like alopecia totalis and universalis, may face a higher risk of cardiovascular disease, though no links were found with specific conditions like ischemic stroke or myocardial infarction.
November 2009 in “Cambridge University Press eBooks” This review discusses the necessity for hair transplant surgeons to be well-versed in both surgical and medical treatments for various forms of alopecia, and it reports no new results.
5 citations
,
January 2015 in “Global Dermatology” This study provides baseline measurements of length, density, form, and angle of eyelashes in Japanese adults in their 20s, which may aid in eyelash reconstruction or treatment for eyelash issues.
26 citations
,
August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.