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Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Finasteride and metformin both help treat PCOS, but using them together works best.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Baicalin may help reduce excessive male hormone levels in PCOS.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

Finasteride effectively treats BPH, but needs more trials to understand potential.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

A woman developed male traits from accidental contact with her husband's testosterone gel.