research The Osler Lecture 2012: Pharmacology 2.0, Medicines, Drugs, and Human Enhancement
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
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research Multi-Ancestry Tandem Repeat Association Study of Hair Color Using Exome-Wide Sequencing
Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
research Study on Autoimmune Thyroid Disorders in Chronic Spontaneous Urticaria at a Tertiary Care Central Rural Hospital in India
People with chronic hives should be tested for thyroid autoimmunity to manage their condition better.
research Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis
Vitamin D3 deficiency is common in Pakistanis with diffuse hair fall, and early treatment is advised.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation
Inducing survivin in normal tissues can protect against radiation damage.
research Free Testosterone Levels in Patients with COVID-19 and Its Association with Disease Severity
People with lower levels of free testosterone tend to have worse COVID-19 outcomes.
research A Case of Sarcoidal Foreign Body Reaction to Permanent Makeup: The Involvement of M2 Macrophages
Steroid injections improved symptoms and hair regrowth in a woman with a reaction to permanent makeup.
research Comprehensive Insight Into Cutaneous Application of Hemp
Hemp is a promising ingredient for skin products due to its healing and soothing properties.
research Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety
CBD may improve skin and hair health, but its effective use and safety need more research.
research Cellular Retinol-Binding Protein-1 Expression Increases with Clinical Severity of Alopecia Areata
Higher CRBP1 levels are linked to more severe alopecia areata.
research Clinical Case of Alopecia Totalis in Pediatric Practice
An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
research Alopecia Universalis After Sitagliptin Intake
A patient's hair loss may be linked to their diabetes medication, Sitagliptin.
research Various Applications of Tofacitinib and Ruxolitinib in Dermatology and Rheumatology: A Review of Current Evidence and Future Perspective
Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Three-Dimensional Cultured Human Dermal Papilla Cells in HGC-Coated Environments Enhance Hair Regeneration and Artificial Skin Integration
3D-cultured cells in HGC-coated environments improve hair growth and skin integration.
research Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research Semecarpus Anacardium Linn. Leaf Extract Exhibits Activities Against Breast Cancer And Prolongs The Survival Of Tumor-Bearing Mice
Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
research Secretome of Bovine Umbilical Vein Endothelial Cells Promotes Wound Healing Regeneration in Second Degree Rat Model Burn Injury
Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.
research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Clinical Success and Ethical Acceptability of Adult Stem Cells in Regenerative Medicine
Adult stem cells are effective and ethically acceptable for treating various diseases.
research Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research Bioactives in Chinese Proprietary Medicine Modulate 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Comparison of QR 678 and QR 678 Neo as Monotherapy and Combination Therapy with 5% Minoxidil Solution and Oral Finasteride in the Treatment of Male Androgenetic Alopecia—Which Is Better?
Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
research Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker
A genetic marker linked to a type of hair loss was found in most patients studied.
research Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Braicitinib Treatment Reduced the Expansion of CD8+ T Cells in C3H Mice With Skin Grafts-Induced Alopecia Areata
Baricitinib treatment helped reduce hair loss symptoms in mice by decreasing inflammation-related immune cells.