research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
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research The Potential of Regulatory T Cell-Based Therapies for Alopecia Areata
Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance
T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
research Improved Humoral Immunity and Protection Against Influenza Virus Infection With a 3D Porous Biomaterial Vaccine
A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients
Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research Regulatory T Cells in Skin Regeneration and Wound Healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research Current Management Strategies for Cutaneous T-Cell Lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Dietary Supplementation With L-Glutamine Enhances Immunity and Reduces Heat Stress in Hanwoo Steers Under Heat Stress Conditions
Adding L-glutamine to the diet of Hanwoo steers may boost their immune system and help them cope with heat.
research Altered Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells from Patients with Alopecia Areata
Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.
research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Feline Atopic Dermatitis: A Retrospective Study of 45 Cases (2001–2012)
Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases
Targeted cytokine treatments may help with alopecia areata, but more research is needed.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Volatile Organic Compounds: A Proinflammatory Activator in Autoimmune Diseases
Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.
research Stress and Psychoneuroimmunologic Factors in Dermatology
Stress and emotional factors can worsen skin conditions by affecting the immune system.
research Topical Minoxidil Treatment for Congenital Alopecia in Hypohidrotic Ectodermal Dysplasia
Minoxidil cream can safely treat hair loss in kids with ectodermal dysplasia.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
Hair follicles help attract immune cells to the skin during stress.