June 2026 in “Mediterranean Journal of Hematology and Infectious Diseases” This case study reports a 15-year-old girl from a visceral leishmaniasis-endemic area in Greece presenting with various symptoms, including high fever, morning joint pain, and blood in urine, eventually leading to findings like rash, anemia, and kidney issues. Results are not detailed in this abstract.
53 citations
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December 2015 in “JAMA Dermatology” This study found that hirsutism and acanthosis nigricans are the most reliable skin markers for diagnosing polycystic ovary syndrome in women and suggest a need for further evaluation of possible metabolic issues.
1 citations
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February 2025 in “Frontiers in Medicine” This study found that patients with juvenile-onset systemic lupus erythematosus have a high prevalence of endocrine and metabolic comorbidities, particularly dyslipidemia and obesity-related issues, suggesting the need for routine monitoring and obesity prevention.
This review examines the potential of CAR-T cell therapy as a transformative treatment for refractory autoimmune diseases, highlighting its mechanisms, clinical challenges, and promising strategies for precision immunotherapy despite issues like complex manufacturing and antigen escape.
73 citations
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June 2010 in “PLoS Genetics” This study identified that a deficiency in the palmitoyl transferase enzyme, due to a mutation in the Zdhhc13 gene, led to severe physiological abnormalities in mice, including skin, bone, and systemic amyloid issues.
Hair loss should be medically treated, as non-medical treatments are ineffective and hair loss can indicate serious health issues.
10 citations
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July 2021 in “International Journal of Rheumatic Diseases” This review summarizes evidence indicating that body image issues in patients with systemic lupus erythematosus should be addressed with the same importance as physical symptoms like pain and disability.
22 citations
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August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
March 2024 in “International journal of molecular sciences” This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.
213 citations
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June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.
100 citations
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July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
12 citations
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October 2018 in “International Journal of Women's Dermatology” This review discusses lesser-known concerns in transgender dermatology, including neovaginal issues, neoplastic and autoimmune conditions, and the effects of unapproved injectable substances, but reports no new clinical findings.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential of microneedles as a pain-free drug delivery method that improves medication distribution while addressing issues associated with traditional transdermal formulations.
April 2018 in “Asian-Australasian journal of bioscience and biotechnology” This study conducted at Madras Veterinary College found that tick infestation was the most frequent diagnosis among hospitalized dogs with dermatological issues, with ectoparasiticides prescribed in 73% of cases.
June 2011 in “The Journal for Nurse Practitioners” This review discusses different types of hair loss in women and suggests that addressing underlying health issues or stopping trigger medications can restore hair growth without additional intervention, but it reports no new results.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” This review summarizes major surveys on Behcet's disease, highlighting its systemic manifestations, with primary morbidity linked to ocular involvement causing severe vision loss or blindness.
2 citations
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November 1998 in “Journal of The European Academy of Dermatology and Venereology” This study focused on the ultrastructural and immunohistochemical aspects of dermal mast cells in systemic mastocytosis and their interaction with the epidermal melanin unit.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Aging affects hair density and skin health, and Behcet's disease, a complex condition with no specific test, involves sores and systemic issues, treated with various medications.
94 citations
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January 2007 in “Cutaneous and Ocular Toxicology” This review discusses the long-term cutaneous and ocular complications from sulfur mustard exposure in the Iranian population, identifying pruritus and malignant changes as significant issues and highlighting eye surface damage leading to visual decline.
39 citations
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October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
7 citations
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July 2019 in “Clinics in Dermatology” This review discusses various systemic diseases associated with secondary alopecia and reports no new clinical findings; it emphasizes the importance of addressing underlying conditions and using diagnostic tools like trichoscopy and histopathology.
6 citations
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January 2016 in “Menopause” Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
This review discusses the generally well-tolerated use of PRP and microneedling, detailing mild adverse events like transient pain and rare severe complications such as irreversible blindness, emphasizing the need for proper technique and precautions to prevent these issues.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that corticosteroids effectively treat vasculitis allergica in over 90% of cases, with long-term kidney issues being the main adverse outcome.
December 2022 in “Small methods” This study developed dissolving microneedles incorporating a new AR degrader for treating androgenetic alopecia, showing that a single application leads to superior hair regeneration compared to daily minoxidil, without systemic toxicity or androgen-related issues.
December 2021 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, androgenetic alopecia patients exhibited more nailfold capillary abnormalities, suggesting a potential link between microcirculation issues and the condition.
January 2015 in “Springer eBooks” Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
33 citations
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January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
23 citations
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July 2015 in “Encyclopedia of Life Sciences” This article discusses systemic lupus erythematosus (SLE) as a complex chronic inflammatory condition with a variable clinical course, impacting multiple organs, and reports no new research findings.
22 citations
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November 2018 in “Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry” This study reviewed the initial clinical presentation of SLE patients in Oman, revealing diverse symptoms and highlighting the importance of nationwide collaboration for effective management of the condition.