This paper argues that for lupus management, selective immunotherapies like anifrolumab and belimumab, which specifically target parts of the immune system, offer more effective treatment options compared to older, broad immunosuppressive strategies.
49 citations
,
February 2009 in “Clinical Rheumatology” This study observed that systemic lupus erythematosus may not be as uncommon among African Blacks as previously reported, highlighting the need for early aggressive treatment.
33 citations
,
August 2013 in “Lupus” This retrospective study observed that while systemic lupus erythematosus patients at King Fahd Hospital in eastern Saudi Arabia had similar clinical manifestations to those in other regions, there were differences in age of onset and sex distribution.
23 citations
,
July 2015 in “Encyclopedia of Life Sciences” This article discusses systemic lupus erythematosus (SLE) as a complex chronic inflammatory condition with a variable clinical course, impacting multiple organs, and reports no new research findings.
11 citations
,
February 2012 in “Pediatrics in Review” This article reviews systemic lupus erythematosus (SLE) and highlights the FDA approval of belimumab, marking the first new SLE treatment in nearly 50 years, but reports no new clinical trial results.
3 citations
,
January 2013 in “Journal of the European Academy of Dermatology and Venereology” This letter to the editor discusses a previous clinical and histopathological analysis of four cases of severe diffuse non-scarring hair loss in systemic lupus erythematosus, reporting no new study results.
1 citations
,
January 2021 in “Arthritis Research & Therapy” The study reported a 7.80% prevalence of scarring alopecia in Chinese SLE patients and identified several risk factors, including mucocutaneous lesions and high disease activity, while renal and cardio-respiratory involvements were negatively associated with it.
In this clinical case study, a 30-year-old man with systemic lupus erythematosus was diagnosed with both catastrophic antiphospholipid syndrome and acquired haemophilia A, successfully treated with immunosuppressive therapy, plasma exchange, and IVIG, leading to a favourable outcome.
December 2023 in “Revista de la Facultad de Ciencias Médicas (Quito)” This case report describes a 15-year-old female whose initial systemic lupus erythematosus manifestations were fever and rash appearing separately, illustrating diagnostic challenges between SLE and infection.
October 2023 in “F1000Research” This case report describes a 21-year-old woman with systemic lupus erythematosus who developed tuberculous lymphadenitis, highlighting the increased risk of TB in patients on long-term immunosuppressive therapy.
August 2023 in “Rheumatology” In this case report, researchers describe a 17-year-old African male with an overlapping condition of juvenile dermatomyositis and systemic scleroderma, highlighting the importance of thorough history-taking and physical examination for accurate diagnosis and suggesting early referral to a pediatric rheumatologist to prevent severe outcomes.
June 2023 in “F1000Research” This case report describes a 21-year-old female with systemic lupus erythematosus who developed tuberculous lymphadenitis, which was attributed to her compromised immune system from long-term immunosuppressive therapy.
November 2021 in “Frontiers in medicine” This case study documents the first reported instance of bullous lichen planus/systemic lupus erythematosus overlap syndrome with initial hair loss, which improved with treatment including glucocorticoids and immunosuppressive drugs.
11 citations
,
September 2022 in “The Journal of Rheumatology” This article discusses the classification and significance of cutaneous manifestations in systemic lupus erythematosus, emphasizing the importance of recognizing these skin features for disease management, but reports no new clinical results.
3 citations
,
September 2019 in “European Medical Journal” This paper presents a case of scalp sarcoidosis with systemic involvement and notes the importance of dermoscopy in its diagnosis, along with a literature review of 46 alopecia-inducing sarcoidosis cases.
2 citations
,
May 2016 in “Oxford University Press eBooks” This article provides guidance on managing systemic lupus erythematosus without presenting new research findings, emphasizing the role of clinical nurse specialists and the importance of lifestyle modifications and appropriate medication regimens.
46 citations
,
January 2015 in “Pediatric Rheumatology” This review highlights the importance of recognizing mucocutaneous lesions in diagnosing juvenile-onset systemic lupus erythematosus, noting that these lesions often improve with controlled lupus and can indicate disease activity.
38 citations
,
May 2017 in “Medical Science Monitor” This study reported a 2.6% prevalence of myositis in patients with systemic lupus erythematosus, with alopecia, leukopenia, and active disease significantly associated with its development.
1 citations
,
February 2023 in “International Journal of Rheumatic Diseases” This study reported that tuberculosis can mimic lupus-like symptoms, including the production of autoantibodies, which may confuse the diagnosis with systemic lupus erythematosus flares.
May 2023 in “Karnataka Pediatric Journal” This case report details an 8-year-old girl with systemic lupus erythematosus presenting as lupus pancreatitis, whose symptoms improved significantly following glucocorticoid and immunosuppressive therapy.
4 citations
,
January 2019 in “Einstein (São Paulo)” In this case report, a patient with severe atopic dermatitis experienced significant improvement with dupilumab after other treatments, including immunosuppressive agents, failed to control the disease.
March 2026 in “Journal of Investigative Dermatology” Early diagnosis and tailored treatment are crucial to prevent permanent hair loss and support self-esteem in children with scarring alopecia.
37 citations
,
May 1999 in “Australasian Journal of Dermatology” This review discusses neutrophil-associated and infiltrative scarring alopecias, as well as promising new treatments, but reports no new clinical results.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.
12 citations
,
December 2021 in “Frontiers in Medicine” This study observed that dermatological patients using certain immunosuppressants, like azathioprine and high-dose prednisolone, had a reduced humoral immune response to the Sinovac-CoronaVac COVID-19 vaccine compared to those without such treatments.
7 citations
,
July 2013 in “InTech eBooks” This article describes the various presentations of oral lichen planus and notes it often requires topical or systemic immunosuppressive treatment for associated discomfort, but it reports no new clinical results.
2 citations
,
January 2017 in “International Journal of Trichology” This case report describes the trichoscopic and histological features observed in a 7-year-old boy with morphea en coup de sabre and details the positive response to systemic immunosuppressive therapy.
2 citations
,
January 2004 in “Elsevier eBooks” This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.
January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
research Skin
2 citations
,
January 2011 in “Elsevier eBooks” This review discusses approaches to diagnosing and managing cutaneous manifestations of lupus erythematosus and reports no new clinical results.