Conventional Treatments in Systemic Lupus Erythematosus
May 2016
in “
Oxford University Press eBooks
”
Studysummary This article provides guidance on managing systemic lupus erythematosus without presenting new research findings, emphasizing the role of clinical nurse specialists and the importance of lifestyle modifications and appropriate medication regimens.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
A new diagnosis of systemic lupus erythematosus (SLE) could be daunting for patients, necessitating education and reassurance, often facilitated by clinical nurse specialists. Lifestyle advice, such as sun protection and smoking cessation, was crucial. Mild disease cases, presenting with symptoms like rash, hair loss, and joint or chest pain, were typically managed with symptomatic treatments, including topical corticosteroids, antimalarials, and NSAIDs. Acute flares might require short-term corticosteroids. Lupus nephritis was treated with corticosteroids and immunosuppressants, using oral mycophenolate or low-dose Euro-Lupus intravenous cyclophosphamide to induce remission, and low-dose corticosteroid plus azathioprine or mycophenolate to maintain it. While corticosteroids were effective, their side effects necessitated using the lowest effective dose.
