Conventional Treatments in Systemic Lupus Erythematosus

    May 2016 in “ Oxford University Press eBooks ”
    Anisur Rahman
    TLDR Systemic lupus erythematosus is managed with lifestyle changes, symptomatic treatments, and careful use of medications to control symptoms and flares.
    A new diagnosis of systemic lupus erythematosus (SLE) could be daunting for patients, necessitating education and reassurance, often facilitated by clinical nurse specialists. Lifestyle advice, such as sun protection and smoking cessation, was crucial. Mild disease cases, presenting with symptoms like rash, hair loss, and joint or chest pain, were typically managed with symptomatic treatments, including topical corticosteroids, antimalarials, and NSAIDs. Acute flares might require short-term corticosteroids. Lupus nephritis was treated with corticosteroids and immunosuppressants, using oral mycophenolate or low-dose Euro-Lupus intravenous cyclophosphamide to induce remission, and low-dose corticosteroid plus azathioprine or mycophenolate to maintain it. While corticosteroids were effective, their side effects necessitated using the lowest effective dose.
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