This case report highlights the diagnostic challenge of ANA-negative pediatric SLE in South Asia, emphasizing the need for comprehensive diagnostic criteria and clinical vigilance for early recognition and treatment.
This case report details a 45-year-old woman with SLE who experienced severe leukopenia and hair loss attributed to azathioprine, suggesting the importance of recognizing these potential adverse effects for timely intervention.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
April 2025 in “Current Rheumatology Reviews” This case study highlights the importance of considering systemic lupus erythematosus in young patients presenting with atypical symptoms like periorbital erythema and pancytopenia, as early diagnosis and treatment can lead to remission.
January 2025 in “Indian Dermatology Online Journal” This case report describes a 27-year-old female with systemic lupus erythematosus who presented with chilblain lupus erythematosus and melanonychia striata, emphasizing the rarity of such presentations in SLE patients.
November 2024 in “Deleted Journal” In this case study, a woman with SLE and severe alopecia showed improved hair growth using intralesional triamcinolone, PRP injections, and tacrolimus ointment, highlighting PRP as a potential adjunct therapy for inflammatory alopecia.
June 2024 in “Archives of Medical Science” Telitacicept effectively improved hair regrowth in a woman with lupus and alopecia.
March 2024 in “Poster presentations” This case report describes a 43-year-old woman diagnosed with both Kikuchi-Fujimoto disease and systemic lupus erythematosus, who showed clinical improvement after treatment with glucocorticoids and hydroxychloroquine, highlighting the rare coexistence of these conditions and the ongoing uncertainty about the precise cause of Kikuchi-Fujimoto disease.
February 2024 in “Journal of Paediatrics and Child Health” This case report suggests the co-occurrence of systemic lupus erythematosus and an eating disorder in an adolescent may be linked through shared adolescent stress factors rather than neuropsychiatric lupus, despite algorithmic indications.
January 2024 in “Faculty of 1000 Research Ltd” This report describes a case of digital gangrene as an early manifestation of systemic lupus erythematosus in a 56-year-old man, highlighting it as a rare complication of late-onset SLE.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
November 2023 in “International Journal of Trichology” This case report describes a 19-year-old male with systemic lupus erythematosus presenting with an unusual combination of mucinous nonscarring alopecia and papulonodular mucinosis, noted by mucin deposition in skin lesions, which responded partially to treatment with hydroxychloroquine and prednisolone.
August 2023 in “The American Journal of Medicine” This case report describes a 17-year-old female patient diagnosed with systemic lupus erythematosus, presenting with arthralgia, hair loss, and Raynaud's phenomenon. The diagnosis was supported by elevated ESR and positive autoantibodies, and treatment included hydroxychloroquine and prednisone.
August 2023 in “JAAD Case Reports” This report describes a 57-year-old woman with fibrosing alopecia in a pattern distribution, who experienced hair regrowth with combined treatment including hydroxychloroquine and other topical and oral therapies.
This case report highlights that Tjalma Syndrome may present as a main symptom of systemic lupus erythematosus and should be considered in patients with ascites, pleural effusions, and elevated CA-125 levels.
April 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This case study reported significant improvement in autoimmune-related symptoms, including complete hair regrowth, in a patient with systemic lupus erythematosus and alopecia areata after treatment with the LGS Protocol.
March 2023 in “Authorea (Authorea)” This case report describes a 5-year-old Sudanese boy with systemic-onset juvenile idiopathic arthritis who also exhibited unique cutaneous manifestations and peripheral eosinophilia alongside tinea capitis.
August 2022 in “F1000Research” This case report describes digital gangrene as a rare primary manifestation of late-onset systemic lupus erythematosus in a 56-year-old man, with marked lesion improvement following rituximab treatment.
January 2022 in “Exclusive Real World Evidence Journal” This case report describes a 22-year-old female with systemic lupus erythematous whose primary symptom was vasculitic polyneuropathy, characterized by polyneuropathy and various positive autoimmune markers.
January 2022 in “Faculty of 1000 Research Ltd” This case report documents digital gangrene as an unusual early sign of late-onset systemic lupus erythematosus in a 56-year-old man, which improved with rituximab treatment.
August 2021 in “BMJ Case Reports” This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.
May 2021 in “Biomedical Journal of Indonesia” This case report describes a 20-year-old man diagnosed with Systemic Lupus Erythematosus and lupus hepatitis, who presented with joint pain and skin symptoms and was treated with methyl prednisolone and hydroxychloroquine.
January 2021 in “Anais do Congresso Brasileiro de Reumatologia 2020” In this case report, tofacitinib led to significant improvement in arthritis and partial improvement in alopecia for a female patient with systemic lupus erythematosus, with no observed adverse effects.
This case report details a child with a specific TNFAIP3 mutation manifesting as a severe SLE/SS phenotype, expanding the known phenotype for this genetic variant.
54 citations
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February 2012 in “Pediatrics in Review” This article discusses systemic lupus erythematosus, covering its clinical features, treatments, and the recent FDA approval of belimumab, but does not present new clinical results.
This study in childhood-onset systemic lupus erythematosus (cSLE) patients found significant gender differences, with males exhibiting more serositis, higher anti-DNA antibody prevalence, and renal involvement, while females experienced more hair loss.
3 citations
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September 2019 in “European Medical Journal” This paper presents a case of scalp sarcoidosis with systemic involvement and notes the importance of dermoscopy in its diagnosis, along with a literature review of 46 alopecia-inducing sarcoidosis cases.
January 2024 in “Pakistan Journal of Medicine and Dentistry” This case report describes the co-existence of Celiac Disease and Systemic Lupus Erythematosus in an 18-year-old girl, managed with a gluten-free diet, steroids, and hydroxychloroquine.
46 citations
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January 2015 in “Pediatric Rheumatology” This review highlights the importance of recognizing mucocutaneous lesions in diagnosing juvenile-onset systemic lupus erythematosus, noting that these lesions often improve with controlled lupus and can indicate disease activity.
April 2024 in “Rheumatology” This case report describes a 22-year-old woman whose initial manifestation of systemic lupus erythematosus was vision-threatening vaso-occlusive retinopathy, highlighting the need for early identification and multidisciplinary treatment.