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Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Laser-assisted drug delivery improves hair loss.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Isotretinoin was not effective in treating facial lichen planopilaris.

Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.

Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.

Some patients lost hair after being treated with the drug enoxaparin for a brain vein clot.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Some chemicals and drugs can cause hair loss, which usually grows back after stopping the treatment.

STAR particles can improve the effectiveness of topical hair growth treatments without causing skin irritation.

New methods improve how well skin treatments work by helping drugs get through the skin barrier.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Children with different rheumatologic diseases have specific skin symptoms that can help with diagnosis.