research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
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research Intermittent and Persistent Type 2 Lupus: Patient Perspectives on Two Distinct Patterns of Type 2 SLE Symptoms
SLE patients experience two patterns of non-inflammatory symptoms: intermittent and persistent.
research Treatment of Scleromyxoedema with Hydroxychloroquine
Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.
research Treatment of Satoyoshi Syndrome: A Systematic Review
Corticosteroids are the most effective treatment for Satoyoshi syndrome.
research Severe Hair Loss Associated with Psychotropic Drugs in Psychiatric Inpatients—Data from an Observational Pharmacovigilance Program in German-Speaking Countries
Some psychiatric drugs can cause severe hair loss, especially valproic acid, and it's more likely in women or those with thyroid issues or past hair loss.
research Sudden Onset Hair Loss and Color Change
A man's sudden hair loss and color change to white was diagnosed as alopecia areata and it improved on its own after six months.
research Efficacy of Topical Latanoprost Versus Topical Minoxidil in the Treatment of Alopecia Areata: Clinical and Dermoscopic Study
Latanoprost is more effective than minoxidil for treating alopecia areata.
research Skin Aging and Menopause: Implications for Treatment
Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
research Alopecia Areata and Health-Related Quality of Life: A Systematic Review and Meta-Analysis
Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Hair Breakage as a Presenting Sign of Early or Occult Central Centrifugal Cicatricial Alopecia
Hair breakage may be an early sign of a hair loss condition called CCCA in African American women.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Evaluation of Hair Loss
Detailed patient history and physical exams are crucial for diagnosing hair loss.
research The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Polycystic Ovarian Syndrome (PCOS) Awareness Among Female Students at Qassim University, Qassim Region, Saudi Arabia
Most female students at Qassim University know about PCOS, but there are still misunderstandings about it.
research The Frequency of Alopecia and Quality of Life in High-School Students in Rural Areas of Eskisehir
Hair loss was found in 37.4% of surveyed rural high-school students in Eskisehir, Turkey, affecting their quality of life, especially in general health and mental well-being.
research Serum Levels of Interleukin-1 (IL-1α, IL-1β) in Patients with Alopecia Areata
IL-1α levels are higher in alopecia areata patients, suggesting a role in the disease.
research Autoimmunity in Satoyoshi Disease: A Systematic Review
Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.
research Was It Gold That Shone? Platelet-Rich Plasma Applications, Outcomes, and Safety Considerations
Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
research Telogen Effluvium After COVID-19 Infection: A Case Report
COVID-19 infection may cause hair loss a few months after recovery.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Systemic Minoxidil for Hair Disorders in Pediatric Patients: A Safety and Tolerability Review
Low-dose oral and sublingual minoxidil seem safe for children with hair disorders.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
research Neuropsychiatric Systemic Lupus Erythematosus Presenting as Bipolar I Disorder With Catatonic Features
A girl initially thought to have a psychiatric disorder was later found to have a lupus-related condition, which improved with proper treatment.
research Contemporaneous Onset of Systemic Lupus Erythematosus and Severe Eating Disorder: Neither the Chicken Nor the Egg
Hormonal changes and social stress may link lupus and eating disorders in teens.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone therapy can help postmenopausal women with low sexual desire if monitored carefully.
research Patients With Specific Skin Disorders Affected by COVID-19: What Do Experiences Say About Management Strategies? A Systematic Review
Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.
research Lymphoproliferative Disorders
Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.
research Acute Parenchymal Lung Involvement in a 68-Year-Old Woman with Systemic Lupus Erythematosus, Anemia, and Thrombocytopenia
A 68-year-old woman with lupus and blood disorders improved after increased steroids and immunoglobulin treatment.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.