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      Cutaneous Androgenization - Effluvium, Hirsutism, Acne

      research Kutane Androgenisierung - Effluvium, Hirsutismus, Akne

      January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)”
      This article discusses the role of androgens in skin conditions like acne and alopecia, emphasizing combined systemic and topical therapy approaches, but it reports no new clinical outcomes.
      Medical Management Options for Hair Loss

      research Medical Management Options for Hair Loss

      July 2011 in “Springer eBooks”
      This review discusses both conventional and new pharmaceutical treatments for hair loss, as well as various natural and herbal remedies, but reports no new clinical results.
      Cosmeceuticals

      research Cosmeceuticals

      June 2004
      This article reviews the synthesis and properties of isotretinoin, tazarotene, minoxidil, and finasteride, and reports no new findings.
      Medications and Hair Transplantation

      research Medications and hair transplantation

      November 2009 in “Cambridge University Press eBooks”
      This review discusses the necessity for hair transplant surgeons to be well-versed in both surgical and medical treatments for various forms of alopecia, and it reports no new results.
      Sexual Hormones in Human Skin

      research Sexual Hormones in Human Skin

      305 citations , February 2007 in “Hormone and metabolic research”
      This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
      5α-Reductase Activity in the Prostate

      research 5α-reductase activity in the prostate

      237 citations , December 2001 in “Urology”
      This review discusses the role of 5α-reductase in prostate development and BPH, and reports no new clinical results; ongoing trials are exploring dual isozyme inhibitors for improved treatment efficacy.
      Molecular Mechanisms of Androgenetic Alopecia

      research Molecular mechanisms of androgenetic alopecia

      229 citations , August 2002 in “Experimental Gerontology”
      This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.
      Biology of the Hair Follicle: The Basics

      research Biology of the Hair Follicle: The Basics

      224 citations , March 2006 in “Seminars in Cutaneous Medicine and Surgery”
      This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.
      Androgens and Alopecia

      research Androgens and alopecia

      165 citations , December 2002 in “Molecular and Cellular Endocrinology”
      This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
      Endocrine Control of Benign Prostatic Hyperplasia

      research Endocrine control of benign prostatic hyperplasia

      97 citations , April 2016 in “Andrology”
      This review discusses the etio-pathogenetic factors in benign prostatic hyperplasia and their role in the development of lower urinary tract symptoms but reports no new research findings.
      Male Gonadal Function in Coeliac Disease: Sex Hormones

      research Male gonadal function in coeliac disease: 2. Sex hormones.

      69 citations , February 1983 in “Gut”
      This study found that untreated men with coeliac disease exhibited androgen resistance, potentially linked to sexual dysfunction, which improved as intestinal health improved, a pattern not observed in other chronic illnesses.
      Peripheral Androgens And The Role Of Androstanediol Glucuronide

      research 6 Peripheral androgens and the role of androstanediol glucuronide

      57 citations , May 1986 in “Clinics in endocrinology and metabolism”
      This review found that women with idiopathic hirsutism may have increased 5α-reductase activity, as indicated by elevated levels of a dihydrotestosterone-reduced metabolite, but more research is needed to confirm its clinical relevance as a biomarker.
      46,XY DSD Due to Impaired Androgen Production

      research 46,XY DSD due to impaired androgen production

      54 citations , April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”
      This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
      Male Androgenetic Alopecia

      research Male androgenetic alopecia

      54 citations , July 2002 in “Clinical and Experimental Dermatology”
      This article provides a critical overview of recent discoveries in the genetics and molecular processes involved in androgenetic alopecia, focusing on its polygenic basis and DHT dependency, but reports no new clinical results.
      An Overview of Alopecias

      research An Overview of Alopecias

      53 citations , March 2014 in “Cold Spring Harbor Perspectives in Medicine”
      The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
      Hair Follicles and Associated Glands as Androgen Targets

      research 8 Hair follicles and associated glands as androgen targets

      53 citations , May 1986 in “Clinics in endocrinology and metabolism”
      This review discusses the influence of androgens on hair and sebaceous growth, emphasizing that response may depend more on peripheral sensitivity than on hormone levels; it reports no new empirical results.
      Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia

      research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia

      47 citations , October 2016 in “Molecular and Cellular Endocrinology”
      This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.
      Idiopathic Hirsutism: Androgen Role and Treatment Options

      research Idiopathic Hirsutism*

      47 citations , August 2000 in “Endocrine Reviews”
      This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.
      Dutasteride

      research Dutasteride

      45 citations , January 2008 in “Drugs”
      This study found that dutasteride effectively improved urinary symptoms, reduced acute urinary retention risk, and decreased prostate volume in men with moderate to severe BPH over two years.