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MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Men with a certain baldness pattern at age 40-50 may have a higher risk of aggressive prostate cancer.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

New oral treatment, finasteride, effectively and safely treats common hair loss.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Immune cells are crucial for hair growth and preventing hair loss.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Trazodone might help reverse post finasteride syndrome.

Effective PCOS treatments require targeting specific signaling pathways.

PCOS is a common hormonal disorder with symptoms like irregular periods and excess hair growth, managed with lifestyle changes and medications.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The compounds tested could potentially treat hair loss and alopecia.

The document concludes that new treatments for skin conditions are complex but effective, including spironolactone for female hair loss and propranolol for infantile hemangiomas.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.

Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.

Topical treatments for hair loss can be effective but need careful safety evaluation.

Small injections of dutasteride improved hair thickness in men with hair loss without major side effects.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.