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Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Liposomes could improve how skin care products work but are costly and not very stable.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Photodynamic Therapy is an effective treatment for mild to severe acne.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.