Assessing a Measure for Quality of Life in Patients with Severe Alopecia Areata: A Multicentric Italian Study

    August 2024 in “ Frontiers in Public Health
    Giacomo Caldarola, Giulia Raimondi, Tonia Samela, Luísa Serpa Pinto, Francesca Pampaloni, Michela Starace, Laura Diluvio, Federica DallʼOglio, Emanuele Vagnozzi, Maria Beatrice de Felici del Giudice, Riccardo Balestri, Francesca Ambrogio, Giampiero Girolomoni, Silvia Francesca Riva, Francesco Moro, Laura Atzori, Giuseppe Gallo, Simone Ribero, Oriana Simonetti, Stefania Barruscotti, Valeria Boccaletti, Angelo Valerio Marzano, Luca Bianchi, Giuseppe Micali, Bianca Maria Piraccini, Alessandro Parisi, Damiano Abeni, Ketty Peris
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    TLDR Alopecia Areata severely impacts mental health, causing anxiety and depression, affecting quality of life.
    The study adapted and validated the Skindex-16AA for Italian patients with severe Alopecia Areata (AA), involving 106 patients with a mean age of 40.20 years. Due to poor fit, a revised 8-item version, Skindex-8AA, was developed, showing good psychometric properties, high stability, and reliability. The Skindex-8AA, consisting of Symptoms and Social-Emotional subscales, demonstrated high reliability (McDonald's ω and Cronbach α > 0.86), significant convergent validity with HADS subscales, and adequate test-retest reliability over 4, 12, and 24 weeks. The study supports using Skindex-8AA for assessing quality of life in Italian AA patients and suggests future research with a larger sample.
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