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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Bimatoprost is a safe and effective treatment for making eyelashes longer, thicker, and darker.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

We don't fully understand how sunlight damages different types of hair.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Wound healing insights can improve regenerative medicine.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Applying a specific inhibitor lightens skin and hair color.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.