November 2024 in “Journal of Investigative Dermatology” Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
110 citations
,
January 1995 in “European Journal of Neuroscience” This study found that glycinergic synapses in the rat spinal cord are predominantly associated with gephyrin, though gephyrin may also be present at non-glycinergic synapses.
September 2013 in “Science” In this study, researchers found that undergraduate research experiences improved students' research skills, research self-efficacy, and aspirations for research careers, with self-efficacy partially mediating the effect on career aspirations.
September 2013 in “Science” The document concludes that human astrocytes aid stroke recovery, research confidence affects student career aspirations, collagen affects cancer spread, a microRNA suppresses brain cancer growth, calmodulin regulates water channels, and small magnesium pieces deform differently.
September 2013 in “Science” Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.
September 2013 in “Science” Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.
September 2013 in “Science” This study found that single-crystal magnesium samples smaller than 100 nm exhibited increased plastic deformation due to greater activation of nonbasal planes as local flow stresses approached 2 GPa.
September 2013 in “Science” This article discusses the Doppler effect as illustrated by the sound of a passing police siren but presents no new research findings.
86 citations
,
February 2009 in “Journal of Neuroscience” This study found that during late pregnancy in rats, there is an increase in extrasynaptic GABA A receptor number in granule cells of the dentate gyrus, linked to hormonal fluctuations.
81 citations
,
July 2012 in “Translational Psychiatry” In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.
September 2023 in “Journal of movement disorders” In this study, 27.9% of Parkinson's disease patients reported hair loss, with a higher incidence linked to a daily levodopa-equivalent dose over 448 mg, suggesting an association between dopaminergic medication use and hair loss complaints.
October 2012 in “European Neuropsychopharmacology” This study found that videoconferencing enabled reliable and consistent assessment of negative symptoms in patients with schizophrenia, demonstrating high interrater reliability among blinded independent raters.
August 2021 in “The Journal of Physiology” This study found that GABA can depolarize murine sensory nerve axons via GABAA receptor activation, with the ß3 subunit being crucial to excitability, and that NKCC1 plays a vital role in mediating this effect.
218 citations
,
December 2011 in “Advances in Urology” This review discusses the biochemical properties and clinical significance of 5 alpha-reductase isozymes and reports no new clinical results.
65 citations
,
October 2008 in “Journal of Neuroendocrinology”
30 citations
,
October 2020 in “Nature Communications” This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.
20 citations
,
October 2018 in “Clinical Drug Investigation” This study observed that men receiving dutasteride for benign prostatic hyperplasia did not show significant differences in neuropsychological assessments compared to a control group not on dutasteride.
14 citations
,
March 2017 in “Brain research” This study suggests that ovarian cycle-related progesterone and neurosteroids regulate α2-subunit expression of GABA-A receptors in the hippocampus through a pathway independent of progesterone receptors, potentially affecting brain conditions linked to the menstrual cycle.
7 citations
,
January 2019 in “The Aging Male” This article discusses post-finasteride syndrome as a distinct syndrome related to prolonged use of 5α-steroid reductase inhibitors, noting persistent side effects even after discontinuation and no new research results are reported.
6 citations
,
May 2014 in “Biomarkers and Genomic Medicine” This review discusses Charnoly bodies as biomarkers of cell injury and potential therapeutic targets in neurodegenerative, cardiovascular, and cancer treatments but reports no new clinical results.
4 citations
,
January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
3 citations
,
July 2021 in “Drug Testing and Analysis” This study found that chronic administration of finasteride affected the isotopic composition of testosterone and nandrolone metabolites, impacting the drug-testing outcomes in athletic contexts.
2 citations
,
July 2019 in “Journal of psychology & clinical psychiatry” This article discusses the role of zinc in reducing depression severity and reports no new research findings, emphasizing the need for further investigation into its therapeutic potential.
This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.
December 2021 in “Research Square (Research Square)” This study found that repeatedly collecting hair follicles from individuals with fragile X syndrome is feasible for measuring FMR1 and FMRP levels in both home and office settings.
December 2018 in “Actas urológicas españolas” This study reported that cognitive biopsy diagnosed prostate cancer in 44% of patients with at least one previous negative biopsy, with higher detection rates in lesions classified as PI-RADS 4 and 5.
May 2012 in “Nature Genetics” Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.
January 2008 in “Annals of Nutrition and Metabolism” This study suggests that a specific region upstream of the TGF-β1 gene may play a key role in androgenetic alopecia by regulating gene expression in a cell-specific manner.
79 citations
,
November 2010 in “Journal of Neuroscience” In this study, researchers found that simple hair clipping in mice induced dynamic plasticity and axogenesis in skin sensory axons, linked to follicular activation and HGF signaling.
1 citations
,
January 2001 in “PubMed” This study proposes that the terminal tuft structure in sensory nerve endings, involving Schwann cell processes and axon fingers, potentially plays a role in mechano-electric transduction in rats.