TLDR A new imaging method helps see and study touch nerve endings in mouse skin.
This study introduces a two-photon imaging technique to visualize low-threshold mechanoreceptor (LTMR) axon terminals in the forepaw skin of mice. This method allows for high-resolution, repeated imaging of axons in intact skin, facilitating the study of LTMR development, patterning, and plasticity over time. It offers a novel platform for observing the assembly and repair of touch circuits, providing valuable insights into somatosensory axon structure and function.
5 citations
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56 citations
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