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This study found that Piezo2 channels are primarily located on sensory axon membranes in mechanosensory end organs, supporting a model where mechanical stimuli activate Aβ RA-LTMR neurons via axon protrusions.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

This study suggests that apoE4 may contribute to cognitive decline by reducing androgen receptor levels in the brain, but androgen treatment improved memory deficits in female mice expressing human apoE4.

This article reviews the scientific exploration of Ayurvedic medicinal plants and discusses their modern applications, such as a drug developed from Commiphora wightti for lipid disorders, without reporting new clinical findings.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

This review discusses the progress in identifying stem cells responsible for tissue regeneration and highlights technological advances in tracking their behavior, but reports no new clinical results.

This study found that sympathetic nerves and arrector pili muscles form a niche that modulates hair follicle stem cell activity, revealing their role in hair follicle regeneration.

This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.

This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.

This study found that patients with post-finasteride syndrome exhibited major depressive disorder, severe erectile dysfunction, and neuropathy, alongside altered neuroactive steroid levels in cerebrospinal fluid.

This review discusses the use of 5α-reductase inhibitors in treating benign prostatic hyperplasia, highlighting their long-term effectiveness and benefits when combined with α1-adrenergic antagonists; it reports no new clinical results.

This study identified chemokine receptor ligands cxcl10 and cxcl11 as new hair-specific transcriptional targets of the Eda pathway, suggesting chemokine signaling plays a role in primary hair follicle patterning.

This study reported that a low color temperature light (1900 K) may have positive effects on melatonin secretion, eye protection, wound healing, and hair regeneration compared to higher temperature lights.

In this case series, four adults developed severe, disabling multisymptom illness potentially linked to fluoroquinolone use, which persisted and progressed even after discontinuation of the drug.

This study found that finasteride treatment in male rats led to enduring effects on depressive-like behavior, hippocampal neurogenesis and neuroinflammation, and gut microbiota composition after withdrawal.

This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.

This study of FAERS data suggests that finasteride, particularly at the 1 mg dosage, is associated with a wide range of adverse effects not previously established in long-term studies, especially among younger men.

This study suggests that neurosteroids and compounds acting on GABA(A) receptors, like THIP, may modulate ethanol intake by influencing drinking patterns.

This review discusses the potential persistent adverse effects associated with 5α reductase inhibitor treatment for androgenetic alopecia but provides no new clinical results; it emphasizes the importance of discussing these risks with patients.

This article investigates whether finasteride influences adult hippocampal neurogenesis related to depression and reports no new clinical findings; the authors suggest further research on its neurosteroid inhibition.

This review discusses the complexity of neuroactive steroid therapies for neuroprotection and reports no new clinical findings, suggesting potential unexpected effects in the brain compared to systemic levels.

This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.

This study found that Dutasteride, a 5α-reductase inhibitor, demonstrated neuroprotective effects by preventing the MPTP-induced decline of dopaminergic markers in a Parkinson's disease mouse model.

In this study, 65% of men with persistent sexual side effects after stopping finasteride reported a reduction in alcohol consumption, echoing findings in rodent models.

This study found that progesterone significantly delayed epileptogenesis development in a mouse model, and its effects were inhibited by finasteride, highlighting the potential role of neurosteroids in modifying epilepsy progression.

This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.