118 citations,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
55 citations,
November 2004 in “Expert opinion on drug safety” Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
27 citations,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
11 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
2 citations,
December 2008 in “Clinical and Experimental Dermatology” A small forehead lesion led to the discovery of a significant brain arteriovenous malformation in a young girl.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
1 citations,
October 2013 Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
238 citations,
July 2003 in “British Journal of Plastic Surgery” Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.
232 citations,
January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
78 citations,
June 2005 in “Annals of oncology” Cetuximab can cause excessive eyelash growth.
69 citations,
January 2015 in “Current problems in dermatology” Trichoscopy is a quick, noninvasive method to diagnose hair and scalp disorders, often reducing the need for biopsies.
43 citations,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
41 citations,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
39 citations,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
30 citations,
June 2021 in “British Journal of Dermatology” Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
19 citations,
August 2011 in “Facial Plastic Surgery Clinics of North America” Hair grafting is a key method for improving scars, especially in areas with hair, by transplanting hair to hide the scar while maintaining its original characteristics.
17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
17 citations,
October 2017 in “Scientific reports” Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
9 citations,
January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
9 citations,
April 2016 in “Cutaneous and ocular toxicology” Alpha Lipoic Acid helps protect skin from smoking damage.
6 citations,
May 2016 in “British Journal of Dermatology” Botulinum toxin A effectively treated a man's facial cysts with no side effects and lasting results.
4 citations,
January 2014 in “Indian dermatology online journal” Monilethrix is a genetic hair disorder causing fragile, beaded hair with no effective treatment.