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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

The skin and thymus develop similarly to protect and support immunity.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.