73 citations
,
June 2003 in “Journal of the American Academy of Dermatology” This article reviews common hair-care practices among African American patients and discusses how these practices relate to hair and scalp disorders, without presenting new clinical research.
70 citations
,
February 2019 in “The journal of immunology/The Journal of immunology” This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.
66 citations
,
June 2015 in “Aesthetic Plastic Surgery” This review of 47 studies indicates that platelet preparations may significantly enhance cellular activity, wound healing, and facial aesthetic outcomes in facial plastic surgery, though potential publication bias should be considered.
66 citations
,
July 2003 in “International Journal of Dermatology” This study found that betamethasone valerate foam was more effective and well-tolerated than betamethasone dipropionate lotion in treating mild-to-moderate alopecia areata, with higher hair regrowth rates observed.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
53 citations
,
October 2012 in “The FASEB Journal” This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.
47 citations
,
June 2019 in “Nature Communications” This study found that self-noncoding dsRNA activates TLR3 to stimulate intrinsic retinoic acid synthesis, promoting new hair follicle formation in wounded mice and showing similar gene expression changes in humans treated with rejuvenation lasers.
44 citations
,
February 2016 in “Science” Researchers developed a new type of memory using antiferromagnets that is stable, not disrupted by magnets, and works at room temperature.
44 citations
,
February 2012 in “The journal of neuroscience/The Journal of neuroscience” This study observed that Ptprq mutant mice exhibit significant abnormalities in hair bundle structure and vestibular dysfunction, suggesting similar issues may contribute to hearing loss and vestibular problems in humans with PTPRQ mutations.
42 citations
,
February 2016 in “Science” The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.
36 citations
,
February 2004 in “International Journal of Dermatology” Different sports can cause specific skin conditions that need proper diagnosis and treatment.
34 citations
,
July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
33 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
33 citations
,
June 2007 in “International Journal of Pharmaceutics” This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.
32 citations
,
November 2020 in “Nanomaterials” This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
32 citations
,
December 2018 in “Cytokine” This review discusses the involvement of type I interferons in skin autoimmune and inflammatory diseases but reports no new clinical results.
31 citations
,
January 2003 in “Dermatology” This article provides an overview of recent discoveries about steroidogenic enzymes involved in androgenetic alopecia but reports no new clinical results.
28 citations
,
September 2008 in “Current Pharmaceutical Design” This review discusses hypersensitivity reactions to anticoagulants like ASA and heparins, highlighting their rare but potentially life-threatening nature, and emphasizes the need for meticulous allergy testing to find safe alternatives.
23 citations
,
July 2008 in “British journal of dermatology/British journal of dermatology, Supplement” This review discusses the use of contact sensitizers for topical immunotherapy in dermatological conditions such as alopecia areata and viral warts, but it reports no new clinical findings.
22 citations
,
September 2015 in “Clinical lymphoma myeloma & leukemia/Clinical lymphoma, myeloma and leukemia” This review describes the various cutaneous manifestations of essential thrombocythemia and how treatments like hydroxycarbamide, interferon-alfa, and anagrelide may lead to skin complications, but does not report new clinical findings.
21 citations
,
January 2003 in “Seminars in reproductive medicine” This review outlines the underlying pathophysiology and treatment options for the androgen excess and reproductive and metabolic manifestations of polycystic ovary syndrome, but reports no clinical results.
20 citations
,
September 2016 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the addition of skin cancer caused by UV irradiation to the list of occupational diseases in Germany and reports no new clinical results.
19 citations
,
October 2014 in “Veterinary Dermatology” Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.
17 citations
,
August 2019 in “Frontiers in Immunology” This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.
17 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
15 citations
,
March 2020 in “Journal of cosmetic dermatology” This review examines non-surgical methods for rejuvenating the periorbital area and highlights the growing role of platelet-rich plasma, but it reports no new clinical findings.
14 citations
,
April 2019 in “Saudi pharmaceutical journal” This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.
14 citations
,
January 2018 in “Endocrine” This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.
14 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.