December 2025 in “International Journal of Innovative Technologies in Social Science” This narrative review assesses evidence on the role of oral supplements in reducing common side effects caused by isotretinoin treatment for acne vulgaris, with the aim of providing guidance for enhancing treatment tolerability.
In this study, FemmeBalance significantly alleviated several PMS symptoms, including physical discomfort and mood disturbance, while also enhancing skin health and social functioning, suggesting it might serve as a viable alternative to traditional PMS treatments.
September 2025 in “Clinics and Practice” This study found that six-month supplementation with fish-derived collagen peptides, calcium, and vitamin D3 improved skin hydration and elasticity and reduced hair loss in menopausal women, with collagen playing a dominant role in enhancing skin elasticity.
September 2025 in “Animals” In this study, cats fed trace minerals complexed with lysine and glutamic acid displayed temporary improvements in hair loss and dander scores at 45 days, compared to those receiving inorganic trace minerals, although no differences were seen by day 90.
July 2025 in “Nutrición clínica y dietética hospitalaria/Nutrición clínica, dietética hospitalaria” This study reviewed various supplements for treating androgenetic alopecia and found that Serenoa repens shows the strongest evidence for use as a single treatment, while ketoconazole may help as an adjunct. Other supplements like zinc, vitamin D, and biotina are not recommended unless deficiencies exist.
July 2025 in “Food Science & Nutrition” This study found that vitamin D supplementation in diets of Rex rabbits improved hair follicle development and fatty acid metabolism, with 1400–2100 IU/kg proving most effective for hair density and 2800 IU/kg increasing hair length.
July 2025 in “Future Journal of Pharmaceuticals and Health Sciences” This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.
May 2025 in “Clinical Cosmetic and Investigational Dermatology” In this clinical study, the researchers found that a standardized wheat polar lipid complex, in both oil and powder form, significantly reduced hair shedding and improved hair growth in 99 women with acute telogen effluvium over 56 to 84 days.
February 2025 in “Animals” This study found that senior dogs fed amino acid-complexed and lysine-glutamic acid-complexed trace minerals had longer, faster-growing hair and increased activity compared to those fed inorganic trace minerals.
February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
January 2025 in “MEDS Public Health and Preventive Medicine” In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.
December 2024 in “Journal of the International Society of Sports Nutrition” In this narrative review, researchers examined common misconceptions and questions about creatine monohydrate, addressing issues such as its potential effects on muscle benefits without exercise, interactions with caffeine, inflammatory properties, safety during pregnancy, and effects on adolescents, among others.
This study observed that women with PCOS have a higher likelihood of vitamin D deficiency, particularly if they are obese, compared to women without PCOS.
April 2024 in “International Journal of Chemical and Biochemical Sciences” This study found that 83% of community participants use cosmetic nutritional supplements, with awareness of their appropriate use suggested to be increasing, as 73% took them after lab tests and 58% followed medical prescriptions.
September 2023 in “Baylor University Medical Center Proceedings” This study reviewed the effectiveness of natural treatments like pumpkin seed oil and rosemary oil for androgenetic alopecia and found them potentially effective with minimal side effects compared to standard treatments like minoxidil. However, more research is needed to confirm their efficacy.
July 2023 in “Plastic and Aesthetic Nursing” Biotin and collagen may help improve hair health.
June 2022 in “Research journal of topical and cosmetic sciences” This study found that taking 500mg of Trichovitals® daily for 12 weeks was linked to significant improvements in hair thickness, reduced hair loss, and enhanced hair growth in young adults.
January 2020 in “University of the Western Cape Electronic Theses and Dissertations Repository (University of the Western Cape)” This study explored dietary supplement use in Gaborone, Botswana's fitness community, finding widespread use especially among educated young adults and limited awareness of potential side effects.
124 citations
,
March 2012 in “JAMA” This abstract discusses the unclear role of dihydrotestosterone (DHT) in postembryonic life in marsupials and possibly humans, reporting no new findings.
46 citations
,
December 2010 in “PubMed” This study demonstrated that tocotrienol supplementation increased hair number in individuals with hair loss compared to a placebo, likely due to its antioxidant effects.
23 citations
,
January 1991 in “Journal of Animal Science” In this study, dietary biotin supplementation showed no significant benefit on reproductive performance in sows or pre-weaning growth and mortality in piglets.
22 citations
,
September 2008 in “Brain & development” In this study on rats, valproic acid was associated with reduced biotinidase enzyme activity and higher alopecia rates, but biotin supplementation did not significantly affect alopecia occurrence.
13 citations
,
January 2019 in “Journal of the American Academy of Dermatology” This study found that biotin supplementation is common among patients at a dermatology clinic despite a lack of evidence for its dermatologic benefits and potential interference with lab tests.
9 citations
,
July 2014 in “PubMed” This review examines the scientific evidence behind alternative treatments for female pattern hair loss and androgenetic alopecia, such as biotin, caffeine, and melatonin, but provides no new clinical results.
5 citations
,
July 2018 in “Pediatrics” This case report describes a previously healthy 3-year-old girl who developed scurvy symptoms not directly linked to vitamin C dietary deficiency, highlighting the potential for misdiagnosis in similar cases.
5 citations
,
January 2012 in “Journal of nutrition & food sciences” This study found that a nutritional supplement containing peptides, lipids, hyaluronic acid, and collagen improved skin, hair, and nail dryness, with significant benefits noted for those with severe symptoms.
3 citations
,
May 2024 in “Frontiers in Physiology” In this study, male rats with spinal cord injury that received either E2 or DHT supplementation both showed restored expression of respiratory neuroplasticity following acute intermittent hypoxia, with E2 also enhancing overall breathing recovery.
3 citations
,
March 2022 in “International Journal of Trichology” This study found that nutritional supplementation with hydrolyzed collagen, amino acids, vitamins, and minerals significantly improved hair anagen/telogen ratios and hair density in telogen effluvium patients.
1 citations
,
July 2022 in “Clinical and Experimental Dermatology” This study suggests that arginine and cysteine deficiency is not present in women with chronic telogen effluvium, indicating that amino acid supplementation may be unnecessary in nutrient-replete populations.
1 citations
,
July 2017 in “Nusantara bioscience” This study found that supplementation with Aloe vera and Spirulina fusiformis effectively improved the appearance of rabbit skin tissue, particularly in hair texture and skin attributes.