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Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Stem cell self-renewal is complex and needs more research for full understanding.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

K6hf is a unique protein found only in a specific layer of hair follicles.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

New treatments targeting specific genes show promise for treating keratin disorders.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Hair shedding is an active process that could be targeted to treat hair loss.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.