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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Molybdenum nanoparticles could be a new treatment for hair loss, working differently than minoxidil.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Daily low-dose aspirin lowers minoxidil's effectiveness for hair loss treatment.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Bariatric surgery improves skin conditions and metabolism but may cause nutritional deficiencies and hair loss.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.

The article concludes that schoolchildren and adolescents experienced various skin issues during the COVID-19 pandemic, including acne from masks and other skin reactions from the virus and vaccines.

Using more than 5% minoxidil can help hair growth more, but results vary and side effects may increase.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

Best hair growth results from combining finasteride and minoxidil.

Apoptosis is crucial for healthy skin and treating skin diseases.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.