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In this study, researchers identified a highly reactive, isozyme-specific sequence for TGase 3, contributing to understanding its distinct functional role and activity distribution in the mouse epidermis.

This study identified nine pathogenic variants in the PADI3 gene and variants in the S100A3 and TCHH genes in patients with central centrifugal cicatricial alopecia, suggesting a broader genetic basis for the disease and potential targets for genetic testing and therapies.

This study identified nine pathogenic variants in the PADI3 gene, and variants in the S100A3 and TCHH genes, which may disrupt protein function and contribute to central centrifugal cicatricial alopecia.

Genetic changes in specific proteins contribute to hair loss in some women of African descent.

This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.

This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.

This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.

This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.

This study found that a peptide treatment using Protein disulphide isomerase improved the mechanical and thermal properties of over-bleached hair by promoting deeper peptide penetration and attachment.

This study reported that bioactive peptides from skin collagen, obtained through selective hydrolysis, improve skin collagen synthesis and remodeling, while inhibiting its breakdown by metalloproteinases, showing benefits such as enhanced skin hydration, elasticity, healing, and hair restoration, without associated adverse effects.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.

This article reviews the role of vasoactive intestinal peptide in maintaining immune privilege in hair follicles and does not report new findings; the authors propose it as essential for immune homeostasis in alopecia areata.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

This study found that a specific fragment of AIMP1, secreted by hair follicle stem cells, activated dermal papilla cells, leading to enhanced hair regrowth and maintenance in mice.

This study found that peptidylarginine deiminase type III and trichohyalin are coincidentally expressed in the infant rat hair follicle, but trichohyalin deimination occurs after their expression during development.

This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.

This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.

This study introduced ElixirSeeker2, a computational framework for designing anti-aging peptides, and found that some newly identified peptides significantly delayed cellular senescence and enhanced cellular and locomotor functions in aged Caenorhabditis elegans.

In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.

This review discusses the roles of adiponectin and bradykinin in skin homeostasis and pathologies, highlighting the need for further research into their therapeutic potential but reports no new clinical results.

This review discusses the potential of using human hair proteomics for non-invasive diagnostic and forensic applications but reports no new results; the authors highlight areas needing further research.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

In this study, fibronectin coating on a low-adhesive substratum increased cell aggregation, growth, and motility, enhancing the formation of hair follicle dermal papilla spheroids.

This study found that human peptidylarginine deiminase type III is the predominant isoform in hair follicles and may modulate structural proteins during hair and hair follicle formation.

This study developed a carbohydrate chitosan-based biomaterial combined with a novel peptide to promote the chondrogenic differentiation of human adipose-derived stem cells, suggesting potential clinical applications for cartilage regeneration.

This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

This study found that citrullinated proteins, which are implicated in rheumatoid arthritis, were abundant in outer membrane vesicles from Porphyromonas gingivalis but nearly absent in mutants, validating their approach to citrullinated peptide identification.