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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Lactate production is important for activating hair growth stem cells.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Sulforaphane from broccoli can help protect skin from sun damage.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Early detection and treatment of iron deficiency in pregnancy are crucial for maternal and infant health.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Hair growth and development are controlled by specific signaling pathways.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.

Cantú syndrome is caused by mutations in the ABCC9 gene.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Dermal adipose tissue in mice can change and revert to help with skin health.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Probiotic bacteria improved skin and hair health in aged mice.

Endocannabinoids help control mast cell activity in human skin.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.