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This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.

In this review, researchers examined the molecular diversity and expression patterns of major skin appendage proteins, like keratins and EDC proteins, in tetrapods, highlighting recent findings in reptiles and birds and identifying knowledge gaps for future research.

This research reports that KCV and its palmitoylated derivatives show strong effectiveness in strengthening hair proteins, indicating their potential for use in advanced hair care products.

The hydrogel dressing effectively treats infected wounds by combining infection control and tissue regeneration.

This study found that keratin 17 expression is initially down-regulated and later strongly up-regulated by ionizing radiation in a rat model, with p53 repressing early transcription.

This study found that a bio-based repair solution containing hydrolysed wool keratin, serine, and transglutaminase improved the physical and chemical properties of damaged hair, increasing its strength, flexibility, and thermal stability while offering long-lasting protection against chemical damage.

In this study, a bleaching protocol was developed to evaluate hair repair products, revealing that K18® and Olaplex® improve hair brightness and lightness, with distinct impacts on hair fiber properties.

This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.

This study found that a chitosan-decorated finasteride nanosystem exhibited satisfactory drug release and retention in rat skin, suggesting it could enhance topical delivery for androgenic alopecia treatment.

This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

In this study, a copolymer made from Tung oil and Tung free fatty acids demonstrated improved mechanical and thermal properties for hair repair, with enhanced resistance and flexibility observed in treated bleached hair, suggesting its potential as a sustainable biopolymer for cosmetic applications.

Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.

Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.

This study found that two eco-friendly analytical methods for quantifying Finasteride and Tadalafil in a new dosage form were effective, green, and suitable for quality control.

This paper reviews the evolution of skin appendages and keratin-associated proteins among amniotes, proposing a model for their genetic divergence without new experimental results.

This study found that the molecular structure of hair is more sensitive to synchrotron X-ray radiation than its supramolecular architecture, indicating potential concerns for biological analyses using such radiation.

This study found that minoxidil suppressed androgen receptor functions and stability, suggesting its potential use in treating diseases related to the androgen-AR pathway.

This study found that TAp63 and ΔNp63 isoforms in the p63 family interact with different transcription factors to regulate distinct transcriptional programs, affecting various biological functions like metabolic pathways, oxidative stress response, and epithelial morphogenesis in mouse epidermal cells.

This study found no significant difference in the tensile properties of hair from different scalp positions, suggesting that microscopic structural heterogeneities may play a role.

This review explores the formulation, characterization, and applications of microemulsions, highlighting their potential for enhanced cutaneous drug delivery by improving bioavailability and enabling sustained release of both hydrophilic and hydrophobic drugs.

This study evaluated the protective effects of a hair conditioner containing rice derivatives on natural Caucasian hair using various analysis methods and found that the conditioner, especially with rice germ oil GX-N, effectively improved hair properties even under stress conditions like irradiation.

In this study, L-cysteine treated with the Trivedi Effect® showed significantly increased isotopic abundance ratios, which may enhance its stability and shelf-life.

This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.

This review examines the role of SET7/9 in non-histone methylation and its implications in various diseases, including cancer, but presents no new clinical results.

This study explored a new dutasteride nanocarrier for alopecia therapy, concluding that ingredient concentration is key to achieving the optimal particle size, stability, and skin permeation for extended drug release.

In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.

This study found that human peptidylarginine deiminase type III is the predominant isoform in hair follicles and may modulate structural proteins during hair and hair follicle formation.

This review discusses the diagnosis, management, and hormone treatment of transsexual individuals, and examines the risks and effects of cross-sex hormone therapy without presenting new clinical results.

This review examines the chemical composition and potential health risks of hair straighteners, but it reports no new findings and emphasizes the importance of understanding hair fibre structure for safe use.