8 citations
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May 2017 in “Current traditional medicine” This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.
January 2024 in “Pediatric rheumatology online journal” In this case report, the authors describe a child and his mother with a heterozygous STING variant linked to SAVI, who exhibited atypical disease courses and varying organ involvement, underlining the diverse clinical manifestations of SAVI.
November 2025 in “EXPERIMENTAL ANIMALS” In this murine study, researchers found that topical treatment with Philippine stingless bee propolis increased folliculogenesis, epidermal thickness, and melanogenesis, but not hair length, potentially supporting hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia models.
June 2021 in “Current Biochemistry” This study determined that a 6.25% concentration of propolis effectively inhibits the growth of dandruff-causing bacteria, with effectiveness values of 223.52% and 99.59% compared to ketoconazole and another propolis extract, respectively.
July 2022 in “Singapore Medical Journal” Most children with alopecia areata improved with treatment, but those with more hair loss had worse outcomes.
33 citations
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April 2020 in “Journal of Clinical Investigation” This study found that hair follicle stem cells from hidradenitis suppurativa patients showed alterations in cell cycle regulation and DNA replication, potentially linking genetic predisposition to the skin inflammation characteristic of the disease.
2 citations
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October 2022 in “Jikken Dobutsu” This study found that Philippines stingless bee propolis extract promotes hair growth in mice by activating the Wnt/β-catenin signaling pathway and stimulating hair follicle development.
November 2025 in “Allergologia et Immunopathologia” This case report documents a rare incident where total alopecia developed within ten days of a bee sting, in the absence of hypersensitivity reactions, suggesting that bee venom may have an immunomodulatory or exacerbating effect on the immune system.
March 2024 in “Cell communication and signaling” This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.
In this study, Urtica dioica L. infusions were used to replace water in k-carrageenan hydrogels, resulting in stronger networks with reduced syneresis and altered textural properties, and the highest antioxidant potential was achieved with specific infusion conditions.
1 citations
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April 2022 in “Annals Academy of Medicine Singapore” This review covers the clinical features and heterogeneity of polycystic ovary syndrome and reports no new findings, emphasizing the need for further research on its complex traits and interactions.
September 2025 in “International Journal of Emergency Medicine” This study reported that the increased dermatological emergency department visits during the pandemic, influenced by PPE usage and psychological stressors, highlight the need for more robust dermatology training and resources in emergency medicine to better prepare for future pandemics.
April 2024 in “Indian Journal of Paediatric Dermatology” This study in Singapore found that alopecia areata generally does not significantly impact the quality of life for pediatric patients and their families, with better outcomes observed in those with comorbidities like allergic rhinitis.
September 2014 in “Archives of disease in childhood” This case report describes a 12-year-old boy who developed severe shingles with skin erosion and hair loss despite early aciclovir treatment after a stem-cell transplant for relapsed acute myeloid leukemia.
1 citations
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January 1997 in “Dermatology” A woman lost her hair from stress after a bee attack and her sister's death.
March 2020 in “Journal of Cosmetic Dermatology” This letter to the editor discusses patient perspectives on androgenetic alopecia treatment at a tertiary dermatology center in Singapore, though results or specific findings are not reported in the abstract.
13 citations
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March 2019 in “Pharmacology Research & Perspectives” This study analyzed CADR reports in Singapore, finding nonsteroidal anti-inflammatory drugs, antibiotics, and iohexol frequently associated with serious skin reactions like rash and angioedema, with trends varying by demographics.
275 citations
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November 2002 in “International Journal of Dermatology” This study found that among an Asian population with alopecia areata, commonly first episodes occurred before age 40, with severe cases linked to psychological effects and treatments showing significant regrowth.
2 citations
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November 2002 in “PubMed” This study found that most Asian patients with androgenetic alopecia in Singapore sought treatment in their thirties primarily for cosmetic reasons, with a strong familial tendency indicating an autosomal dominant inheritance pattern.
June 2021 in “Dermatologic surgery” This review discusses the measurement of patient satisfaction in acne scar treatment studies, highlighting the need for standardized satisfaction questions to enhance comparability and future research; it reports no new clinical results.
August 2019 in “Journal of The American Academy of Dermatology” This study found that bleach baths using 0.005% hypochlorite directly affected serine protease expression in skin cells and reduced skin pH in patients with atopic dermatitis, suggesting potential therapeutic benefits.
24 citations
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April 2021 in “BMC women's health” This study found that women with PCOS and high BMI exhibited significantly increased hair growth compared to non-PCOS women, suggesting an additive effect of body weight on this phenotype in PCOS.
10 citations
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May 2000 in “PubMed” This study found that the prevalence of male androgenetic alopecia in a Singapore community was 63%, increasing with age and showing higher rates among Indians compared to Chinese.
1 citations
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October 2023 in “Frontiers in Oncology” This study presented cases where potentially significant germline variants were unexpectedly found during genomic profiling for myeloid malignancies, discussing the challenges in genetic counseling and management, especially when variants don't match the patient's condition.
69 citations
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July 1997 in “Der Urologe” This study found that PRO 160/120 and Finasteride showed similar effectiveness in improving urinary symptoms and quality of life in patients with benign prostatic hyperplasia over 48 weeks.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
54 citations
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September 2002 in “Annals of Pharmacotherapy” This review discusses various herbal therapies, such as Serenoa repens and Pygeum africanum, for treating benign prostatic hyperplasia, noting their potential but highlighting unresolved questions about their efficacy and safety.
48 citations
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September 2020 in “Frontiers in Immunology” In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.
47 citations
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December 2019 in “Frontiers in immunology” This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.
32 citations
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January 2012 in “Chinese Medicine” In this study, a hydro-alcoholic extract of Urtica dioica demonstrated in vitro antioxidant activity, potentially linked to its ferulic acid content.