May 2023 in “Frontiers in Endocrinology” Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
December 2022 in “Cumhuriyet medical journal” Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.
June 2020 in “Journal of genetic medicine” The document's conclusion cannot be provided because the document is not accessible or understandable.
59 citations,
August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
30 citations,
October 2020 in “Frontiers in Plant Science” Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.
17 citations,
July 2015 in “Biomolecules and Biomedicine” High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.
16 citations,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
10 citations,
January 2019 in “Advances in Clinical and Experimental Medicine” Certain variations in the vitamin D receptor gene are linked to an increased risk of polycystic ovary syndrome.
4 citations,
December 2021 in “Clinical and Experimental Reproductive Medicine” Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
3 citations,
June 2017 in “Reproductive biomedicine online” A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.
October 2023 in “Applied sciences” Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.
September 2023 in “Diagnostics” Low vitamin D levels may affect ovulation and progesterone in infertile women.
May 2023 in “Metabolites” Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.
A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.
May 2023 in “Endocrine, metabolic & immune disorders” Hibiscus rosa-sinensis is used in traditional medicine and is safe in high doses, with various health benefits.
105 citations,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
105 citations,
March 2006 in “Human reproduction” Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
44 citations,
September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
28 citations,
January 2017 in “Indian Dermatology Online Journal” Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.
24 citations,
April 2021 in “BMC women's health” High BMI worsens hair growth in women with PCOS.
24 citations,
April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
21 citations,
December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
20 citations,
November 2019 in “International Journal of Environmental Research and Public Health” Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.
19 citations,
March 2022 in “International Journal of Environmental Research and Public Health” Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.