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Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Dupilumab may cause significant hair loss, which can reverse after stopping the drug.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Lipedematous scalp is mainly caused by an increase in fat tissue under the skin and is different from lipedematous alopecia.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Adalimumab helped control a child's severe eye disease when other treatments failed.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Finasteride causes reduced tear flow and severe eye inflammation.

Skin health and diseases are closely linked to metabolic processes.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.

Cronkhite-Canada syndrome can be diagnosed without gastrointestinal polyps if there is severe mucosal atrophy and edema.

Polypoid cystitis can mimic bladder cancer but can be effectively treated with surgery, stents, and medication.

A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.

Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.

Careful management of steroid use is crucial in pregnant women with bullous pemphigoid to avoid complications like Cushing syndrome.