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Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The study created a new method to test drugs that affect hormone processing in skin.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Vitamin D receptor may help protect against UV-induced skin cancer.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.

DHT stops hair regrowth in mice, similar to human hair loss.

Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.