Search
for

    Did you mean Steroid Metabolism?
    Glossary Steroid Metabolism

    process of breaking down and converting steroid hormones

    Steroid metabolism refers to the process by which the body breaks down and converts steroid hormones, such as cortisol, testosterone, and estrogen, into other substances. This involves a series of biochemical reactions primarily in the liver, where enzymes modify the steroid molecules to make them more water-soluble, allowing for their excretion through urine or bile. Understanding steroid metabolism is crucial for both diagnosing and treating conditions related to hormone imbalances and for the development of steroid-based medications.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    2. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes edoc (University of Basel) · 2014
    3. Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine The Journal of Clinical Pharmacology · 1993 · 9 citations
    4. Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies Psychopharmacology · 2014 · 34 citations
    5. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    6. Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands Figshare · 2026
    7. Behandlung mit Antiandrogenen in der Gynäkologie 1977 · 7 citations
    8. Enzymology of the hair follicle. PubMed · 2001 · 31 citations
    9. Is dehydroepiandrosterone a hormone? Journal of Endocrinology · 2005 · 403 citations
    10. Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency The Journal of Clinical Endocrinology and Metabolism · 2008 · 81 citations
    11. Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs Journal of Dermatological Science · 2012 · 1 citations
    12. Ovine placental steroid synthesis and metabolism in late gestation† Biology of reproduction · 2018 · 9 citations
    13. Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis Journal of Autoimmunity · 2024 · 20 citations
    14. Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1 Journal of Cellular Biochemistry · 2005 · 27 citations
    15. Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands Figshare · 2026
    16. Hormonal status of male reproductive system: androgens and estrogens in the testis and epididymis. In vivo and in vitro approaches. PubMed · 2006 · 43 citations
    17. Roles of steroid sulfatase in brain and other tissues Physiological Research · 2008 · 22 citations
    18. Gas chromatography/mass spectrometry based hair steroid profiling may reveal pathogenesis in hair follicles of the scalp 2011 · 30 citations
    19. Clinical relevance of testosterone and dihydrotestosterone metabolism in women ˜The œAmerican journal of medicine · 1995 · 31 citations
    20. Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids Endocrine, metabolic & immune disorders. Drug targets · 2006 · 26 citations
    21. 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish Communications Biology · 2026
    22. Expression, characterization, and structural analysis of human liver delta4-3-ketosteroid 5beta-reductase (AKR1D1) and its disease-related mutant P133R ScholarlyCommons (University of Pennsylvania) · 2009
    23. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    24. Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X PLOS ONE · 2017 · 18 citations
    25. Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis British Journal of Dermatology · 1997 · 12 citations
    26. Cholesterol homeostasis: Links to hair follicle biology and hair disorders Experimental Dermatology · 2019 · 25 citations
    27. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    28. National consensus on the management of patients with hyperandrogenism (2016) Reproductive Endocrinology · 2016 · 12 citations
    29. PSAT217 Estrogen Deficiency as a Cause of Decreased 1- alpha - hydroxylase Activity Journal of the Endocrine Society · 2022
    30. 5α-reduction of epitestosterone is catalysed by human SRD5A1 and SRD5A2 and increases androgen receptor transactivation The Journal of Steroid Biochemistry and Molecular Biology · 2024 · 14 citations