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MR antagonists may improve skin health and wound healing, especially in aging.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

17β-estradiol can reduce inflammation in the skin.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

DHT affects testicular development and regulates spermatogenesis in some fish.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.