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Spironolactone can reduce hair growth in women with hirsutism.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Artificial sebum L closely mimics human sebum for drug delivery research.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Minoxidil effectively controls blood pressure but side effects may limit its use.

Macrophages help hair growth after injury through CX3CR1 and TGF-β1.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

The U.S. military's teledermatology program was effective in providing fast and successful skin care in remote locations, preventing unnecessary evacuations.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.