January 2025 in “Annals of Dermatology” This study reports that patients with primary cicatricial alopecia have distinct bacterial colonization and higher antibiotic resistance compared to those with non-inflammatory scalp conditions, indicating the importance of bacterial culture and susceptibility testing for targeted therapies.
January 2025 in “Dermatology Research and Practice” This study examines how skin microbiota and the gut-skin axis affect acne development, aiming to reveal mechanisms that could inform future treatment strategies for acne and other inflammatory skin conditions.
January 2025 in “Case Reports in Veterinary Medicine” In this case study, a female European bison calf developed generalized bacterial dermatitis caused by *Staphylococcus aureus*, which improved after targeted treatment, highlighting the need for timely diagnosis and disease management in wildlife conservation.
November 2024 in “Journal of Investigative Dermatology” Changes in scalp bacteria are linked to female hair loss, suggesting new treatment options.
This study of Egyptian patients with alopecia areata found no significant difference in Staphylococcus epidermidis gene expression between patients and healthy controls but reported a negative correlation between Staphylococcus epidermidis expression and the severity of alopecia areata, suggesting potential involvement in disease severity.
September 2024 in “South Eastern European Journal of Public Health” This study found that patients with alopecia areata had increased levels of serum immunoglobulin E and interleukin-13 compared to healthy controls, with additional variation in levels observed across age and weight.
June 2024 in “Current Developments in Nutrition” This study found that a nutritional intervention in dogs led to changes in skin microbiome and immune-related gene expression, with reduced levels of certain fungal pathogens and a potential alleviation of atopic dermatitis symptoms.
June 2024 in “JURNAL BIOLOGI TROPIS” In this systematic literature review, researchers reported that Moringa oleifera Lamk. leaf extract may serve as a potential anti-acne agent, demonstrated by its ability to inhibit the growth of acne-causing bacteria in laboratory settings.
June 2024 in “Indian Journal of Veterinary Medicine” In this case report, a one-year-old male dog with demodicosis, confirmed by the presence of Demodex canis and Staphylococcus bacteria, was successfully treated using ivermectin, amitraz, cephalexin, and vitamin supplements with liver extract.
June 2024 in “Skin Research and Technology” In this study, researchers observed significant differences in microbial composition between UV-induced fluorescent and non-fluorescent scalp areas in patients with androgenetic alopecia, noting a higher abundance of Cutibacterium in the fluorescent regions.
May 2024 in “Journal of cosmetic dermatology” This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.
May 2024 in “Journal of Education, Health and Sport” This review article highlights the complexity of treating folliculitis decalvans, emphasizing the role of systemic antibiotics like rifampicin and clindamycin as common treatments, while also discussing promising novel therapies, including biological agents, that require further clinical trials to assess their effectiveness and safety.
February 2024 in “Journal of applied pharmaceutical research” This study formulated herbal hair oils using extracts such as Coconut and Amla, observing significant improvements in hair growth promotion, antioxidant, and antimicrobial properties in animal models, suggesting potential natural remedies for hair care with further research needed for human application.
This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.
January 2024 in “Medicinska istrazivanja” This case report describes erosive pustular dermatosis of the scalp in a 55-year-old woman, which improved rapidly with oral antibiotics and topical corticosteroids but resulted in permanent scarring alopecia, emphasizing the need for prompt diagnosis and treatment to minimize scarring.
January 2024 in “International Journal of Pharmaceutical Research and Development” This study explored the development of herbal hair gels using natural extracts like flaxseed and guava leaves, targeting the reduction of dandruff and regulation of hair loss through antimicrobial and anti-inflammatory properties, though specific results of efficacy are not reported.
December 2023 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this study, researchers observed that Folliculitis decalvans diagnoses were often delayed, with severe cases linked to hidradenitis suppurativa and Staphylococcus aureus infection, and highlighted the need for better dermatological training to reduce these delays.
November 2023 in “Journal of Investigative Dermatology” Inhibiting EGFR weakens skin's defense against bacteria.
August 2023 in “Veterinary Science and Medicine Journal” In this case study, the researchers diagnosed a young male cat with dermatitis caused by a fungal infection, specifically identifying Penicillium and Aspergillus species, and observed improvement in symptoms following a two-week treatment with grisofulvin, chlorphenamine maleate, and fish oil shampoo.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study identified key trends and influential contributors in skin microbiome research from the past decade, highlighting the growing publication rates, major players like the USA, and prominent researchers such as Gallo RL.
June 2023 in “Benha Journal of Applied Sciences” In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.
April 2023 in “Journal of Investigative Dermatology” This study found that the type 2 cytokines IL-4 and IL-13 may amplify Staphylococcus aureus-induced inflammation and barrier disruption in atopic dermatitis, potentially worsening skin defense against this bacterium.
January 2023 in “Fundamental toxicological sciences” In this study, mozuku-derived ultra-high-molecular-weight fucoidan was found to inhibit the growth of skin bacteria like Staphylococcus aureus but not other tested bacteria such as Cutibacterium acnes.
November 2022 in “Journal of Investigative Dermatology” This study found that sodium butyrate, a metabolite from the HF microbiome, significantly delayed catagen onset and promoted key physiological processes in cultured human hair follicles.
January 2022 in “Journal of pharmacognosy and phytochemistry” This study found that a polyherbal gel made from guava leaves, amla, and aloe is effective against candidiasis on the skin, with additional benefits of nourishing hair and preventing premature graying.
September 2021 in “Pediatrics in review” This case study describes a 7-month-old boy diagnosed with keratitis-ichthyosis-deafness syndrome due to a de novo GJB2 gene mutation, highlighting the challenges in treatment and eventual fatal outcome due to severe complications.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
May 2021 in “British Journal of Dermatology” This review discusses the composition and role of the hair follicle microbiome in health and disease, highlighting that our understanding remains limited and stressing the need for more comprehensive studies.
April 2021 in “Journal of Investigative Dermatology” This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.