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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Fat-related cells are important for initiating hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.