December 2022 in “Gastroenterology” This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.
6 citations
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January 2015 in “Biochemical Society Transactions” This review discusses the role of Ysc84/SH3yl1 proteins in linking actin regulation to membrane morphology changes but reports no new experimental results.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that nanostructured lipid carriers loaded with spironolactone might improve localized delivery to hair follicles for treating androgenic alopecia, potentially minimizing systemic side effects.
July 2025 in “Journal of Investigative Dermatology” Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.
June 2021 in “eScholarship (California Digital Library)”
7 citations
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March 2012 in “European Journal of Pediatrics” This case report describes a 4.5-year-old boy with steroid-resistant nephrotic syndrome linked to X-linked recessive ichthyosis, where remission was achieved using cyclosporine, suggesting STS deficiency as a potential genetic cause of the condition.
January 2025 in “Case Reports in Oncological Medicine” This case report emphasizes the need to consider Sertoli-Leydig cell tumors in the differential diagnosis of adnexal masses in patients with Peutz-Jeghers syndrome, noting that these tumors can present unusually with bilateral adnexal involvement.
September 2021 in “Authorea (Authorea)” This case report describes a middle-aged Sudanese woman with intussusception associated with systemic lupus erythematosus (SLE), presenting with multiple symptoms including joint pain and abdominal issues.
26 citations
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September 2009 in “Psychosomatics” This case report highlights the importance of recognizing that neuropsychiatric symptoms in adolescents may signal the onset of systemic lupus erythematosus rather than a primary psychiatric disorder.
19 citations
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May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
April 2019 in “Journal of Investigative Dermatology” This study reported that in mycosis fungoides and Sezary syndrome, there is male predominance and younger age of presentation in early-stage disease, with significant data collection efforts supporting biomarker identification.
3 citations
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March 2019 in “American Journal of Dermatopathology” This case report presents the first documented instance of basal cell carcinoma and cutaneous leiomyosarcoma occurring as a collision neoplasm in the same biopsy specimen.
8 citations
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February 2022 in “Frontiers in Medicine” This article reports a case of Rowell syndrome in a woman with chronic cutaneous lupus erythematosus that appeared to be triggered by COVID-19 infection, suggesting a potential connection.
17 citations
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May 2007 in “British Journal of Dermatology” This case report describes a child with Gomez–Lopez–Hernandez syndrome, highlighting developmental challenges and medical interventions, yet noting academic success and participation in mainstream activities.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study examines how conditions like PSSD, Long COVID, and ME/CFS form a "Post-Exposure Syndromes" family, initiated by transient exposures but persisting due to complex state-space dynamics, and suggests improving pharmacovigilance to better address and understand these persistent syndromes.
September 2024 in “Portuguese Journal of Dermatology and Venereology” This review discusses central centrifugal cicatricial alopecia, its similarities to lichen planopilaris, and emphasizes the need for further research due to its underdiagnosis and impact on African-descended women.
This study found that the transcription factor Lhx2 regulates Sonic Hedgehog signaling in mouse retinal progenitor cells, mainly by controlling the expression of co-receptors essential for effective pathway activation during early retinal neurogenesis.
1 citations
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March 2022 in “Frontiers in Medicine” This case report highlights a rare instance of esophageal carcinoma in a patient with Cronkhite-Canada syndrome, emphasizing the importance of endoscopic surveillance for malignant gastrointestinal tumors in these patients.
December 2010 in “OhioLink ETD Center (Ohio Library and Information Network)” In this study, total Sry transcript expression in various rat tissues was linked to Acsl3 expression, suggesting that Sry may play a role in regulating fatty acid metabolism.
1 citations
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May 2024 in “The Journal of Sexual Medicine” This case report suggests that clomiphene citrate can effectively restore fertility in some men with a long history of anabolic steroid abuse, though individual responses to treatment vary.
5 citations
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February 2025 in “Cell Reports” In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.
15 citations
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April 2016 in “Medicine” This study reports that systemic lupus erythematosus patients with Evans syndrome often exhibited photosensitivity, hypocomplementemia, and elevated serum IgG, while lupus nephritis was less common, suggesting distinct clinical features.
November 2020 in “Zenodo (CERN European Organization for Nuclear Research)” 26 citations
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June 2024 in “Frontiers in Immunology” The authors discussed that SOCS1 and SOCS3's inhibition of JAKs plays a significant role in the development of JAK inhibitor drugs for skin inflammatory diseases and malignancies.
September 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a germline variant in PLCD1 as a major risk allele for familial trichilemmal cysts, requiring a subsequent somatic mutation in the same allele for cyst formation.
6 citations
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January 2020 in “BMC Medical Genetics” In this study, researchers identified a novel STS gene (c.287G > A; p.W96*) mutation in Pakistani individuals with X-linked ichthyosis, expanding the understanding of its genetic causes and aiding in genetic counseling.
138 citations
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June 2019 in “Stem Cells and Development” This review explores the potential of periodontal ligament stem cells for regenerative therapy in periodontium, despite challenges due to their rarity, and reports no clinical results.
132 citations
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July 2000 in “Lupus” This study found that chronic cutaneous lupus erythematosus with discoid lesions was the most common skin manifestation among patients with lupus erythematosus, while nonspecific skin lesions were linked to systemic lupus erythematosus, particularly during active disease phases.
July 2024 in “Journal of Investigative Dermatology” Human epidermal stem cells divide faster than previously thought.
18 citations
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April 2014 in “Stem cells” The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.