Cronkhite-Canada Syndrome Associated With Superficial Esophageal Carcinoma: A Case Report and Literature Review

    March 2022 in “ Frontiers in Medicine
    Yan Zhao, Fujing Lv, Yang Xun, Yongjun Wang, Shutian Zhang, Peng Li
    TLDR Regular endoscopic checks are crucial for Cronkhite-Canada syndrome patients to catch potential cancers early.
    This case report discusses a 67-year-old man with Cronkhite-Canada syndrome (CCS) who developed early esophageal carcinoma, a rare comorbidity. The patient was treated with endoscopic submucosal dissection for the esophageal lesion and endoscopic mucosal resection for colon polyps, followed by glucocorticoid therapy. The treatment was successful, with no recurrence of esophageal carcinoma and a decrease in gastrointestinal polyps over an 18-month follow-up. The case highlights the importance of regular endoscopic surveillance in CCS patients due to the potential for malignant transformation.
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